Synthetic biology projects in vitro

被引：121

作者：

Forster, Anthony C. ^{[1
]}

Church, George M.

机构：

[1] Vanderbilt Univ, Med Ctr, Dept Pharmacol, Nashville, TN 37232 USA

[2] Vanderbilt Univ, Med Ctr, Vanderbilt Inst Chem Biol, Nashville, TN 37232 USA

[3] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA

来源：

GENOME RESEARCH | 2007年 / 17卷 / 01期

关键词：

D O I：

10.1101/gr.5776007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Advances in the in vitro synthesis and evolution of DNA, RNA, and polypeptides are accelerating the construction of biopolymers, pathways, and organisms with novel functions. Known functions are being integrated and debugged with the aim of synthesizing life-like systems. The goals are knowledge, tools, smart materials, and therapies.

引用

页码：1 / 6

页数：6

共 62 条

[1] An expanded genetic code with a functional quadruplet codon [J].

Anderson, JC ;

Wu, N ;

Santoro, SW ;

Lakshman, V ;

King, DS ;

Schultz, PG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (20) :7566-7571

[2]

[Anonymous], 2004, SYNTHETIC BIOHAZARD

[3] Synthetic biology [J].

Benner, SA ;

Sismour, AM .

NATURE REVIEWS GENETICS, 2005, 6 (07) :533-543

[4] In vitro compartmentalization by double emulsions: sorting and gene enrichment by fluorescence activated cell sorting [J].

Bernath, K ;

Hai, MT ;

Mastrobattista, E ;

Griffiths, AD ;

Magdassi, S ;

Tawfik, DS .

ANALYTICAL BIOCHEMISTRY, 2004, 325 (01) :151-157

[5]

Bjork Glenn R., 1995, P165

[6] Natural and engineered nucleic acids as tools to explore biology [J].

Breaker, RR .

NATURE, 2004, 432 (7019) :838-845

[7]

Brody E N, 2000, J Biotechnol, V74, P5, DOI 10.1016/S1389-0352(99)00004-5

[8] Protein-mediated error correction for de novo DNA synthesis -: art. no. e162 [J].

Carr, PA ;

Park, JS ;

Lee, YJ ;

Yu, T ;

Zhang, SG ;

Jacobson, JM .

NUCLEIC ACIDS RESEARCH, 2004, 32 (20) :e162

[9] Chemical synthesis of poliovirus cDNA: Generation of infectious virus in the absence of natural template [J].

Cello, J ;

Paul, AV ;

Wimmer, E .

SCIENCE, 2002, 297 (5583) :1016-1018

[10] An expanded eukaryotic genetic code [J].

Chin, JW ;

Cropp, TA ;

Anderson, JC ;

Mukherji, M ;

Zhang, ZW ;

Schultz, PG .

SCIENCE, 2003, 301 (5635) :964-967

← 1 2 3 4 5 6 7 →