KLEBSIELLA PNEUMONIAE OXA-48 IN A UROLOGY PATIENT: CASE REPORT

被引：4

作者：

Jajic, Ines ^{[1
]}

Bencic, Ana ^{[2
]}

Siroglavic, Marko ^{[3
]}

Zarfel, Gernot ^{[4
]}

Ruzic, Boris ^{[5
]}

Pezelj, Ivan ^{[5
]}

Bedenic, Branka ^{[6
,7
]}

机构：

[1] Sestre Milosrdnice Univ Hosp Ctr, Dept Microbiol Parasitol & Hosp Infect, Vinogradska C 29, HR-10000 Zagreb, Croatia

[2] Univ Zagreb, Sch Med, Zagreb, Croatia

[3] Zagreb Univ Hosp Ctr, Dept Transfus Med, Zagreb, Croatia

[4] Karl Franzens Univ Graz, Inst Microbiol Hyg & Environm Med, Graz, Austria

[5] Sestre Milosrdnice Univ Hosp Ctr, Dept Urol, Zagreb, Croatia

[6] Univ Zagreb, Sch Med, Dept Microbiol, Zagreb, Croatia

[7] Zagreb Univ Hosp Ctr, Clin Dept Clin & Mol Microbiol, Zagreb, Croatia

来源：

ACTA CLINICA CROATICA | 2017年 / 56卷 / 01期

关键词：

Klebsiella pneumoniae; isolation and purification; Klebsiella infections; Prostatectomy; complications; Case reports; METALLO-BETA-LACTAMASE; ESCHERICHIA-COLI; ENTEROBACTER-CLOACAE; EMERGENCE; OUTBREAK; SPREAD; CARBAPENEMASES; OXACILLINASE; RESISTANCE; IMIPENEM;

D O I：

10.20471/acc.2017.56.01.23

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present an isolate of Klebsiella pneumoniae OXA-48 isolated in a 68-year-old man who underwent radical prostatectomy due to prostate cancer. The antibiotic susceptibility testing to a wide range of antibiotics was performed by disk diffusion method and determination of minimal inhibitory concentrations. The isolate was classified as multidrug-resistant. It showed intermediate susceptibility to imipenem and meropenem, resistance to ertapenem, and sensitivity only to colistin, amikacin, and trimethoprim-sulfamethoxazole. The isolate was positive for ESBLs, negative for AmpC. Polymerase chain reaction and sequencing revealed bla(OXA-48), bla(CTX-M-15) and bla(SHV-11). The plasmid encoding OXA-48 beta-lactamase did not belong to any known PCR-based replicon typing. According to genotyping, the isolate belonged to ST37.

引用

页码：166 / 171

页数：6

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