High-dose therapy in breast cancer:: out of favor but not out of promise

被引：5
|
作者：
Glück, S [1 ]
Stewart, D [1 ]
机构：
[1] Univ Calgary, Tom Baker Canc Ctr, Fac Med, Dept Oncol Med & Pharmacol & Therapeut, Calgary, AB T2N 4N2, Canada
来源：
BONE MARROW TRANSPLANTATION | 2000年 / 25卷 / 10期
关键词：
high-dose chemotherapy; breast cancer; evidence for efficacy; controversy;
D O I：
10.1038/sj.bmt.1702388
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
The evidence for use of high-dose chemotherapy and autologous stem cell transplantation for breast cancer still remains inconclusive at best, A number of prospective randomized phase III studies have been either published or presented recently or are underway in North America and Europe. It will be crucial to complete the available prospective randomized phase III study and obtain the data when all studies reach a mature status. Only then will level I evidence become available to determine the efficacy and effectiveness of high-dose chemotherapy and autologous stem cell transplantation in breast cancer.
引用
收藏
页码：1017 / 1019
页数：3
相关论文
共 50 条
  • [31] FEC mobilized stem cells for high-dose therapy in breast cancer patients
    Lindman, H
    Wiklund, T
    Holte, H
    Ljungman, P
    Blomqvist, C
    Kvalheim, G
    Bengtsson, M
    Höglund, M
    Wilking, N
    Bergh, J
    ACTA ONCOLOGICA, 1999, 38 (02) : 239 - 245
  • [32] No future for high-dose chemotherapy in breast cancer
    Wilkinson, E
    LANCET ONCOLOGY, 2002, 3 (12): : 715 - 715
  • [33] High-dose chemotherapy in metastatic breast cancer
    Leonard, RCF
    LANCET, 1998, 351 (9107): : 986 - 986
  • [34] Disseminated tumour cells in breast cancer patients undergoing high-dose therapy
    Krüger, WH
    Tögel, F
    Kröger, N
    Renges, H
    Arland, M
    Gutensohn, K
    Lindner, C
    Jänicke, F
    Zander, AR
    HIGH-DOSE THERAPY AND TRANSPLANTATION OF HAEMATOPOIETIC STEM CELLS, 2000, : 34 - 38
  • [35] High-dose chemotherapy in resistant breast cancer
    Crown, J
    BREAST, 1996, 5 (04): : 298 - 303
  • [36] High-dose chemotherapy in advanced breast cancer
    Viens, P
    Maraninchi, D
    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2002, 41 (02) : 141 - 149
  • [37] HIGH-DOSE CHEMOTHERAPY FOR BREAST-CANCER
    CARBONE, PP
    JOURNAL OF CLINICAL ONCOLOGY, 1987, 5 (02) : 167 - 168
  • [38] High-dose chemotherapy for advanced breast cancer
    Ahmad, K
    LANCET ONCOLOGY, 2006, 7 (01): : 19 - 19
  • [39] High-dose chemotherapy (CTM) for breast cancer
    Damon, LE
    Wolf, JL
    Rugo, HS
    Gold, E
    Zander, AR
    Cassidy, M
    Cecchi, G
    Cohen, N
    Irwin, D
    Tracy, M
    Ries, CA
    Linker, CA
    BONE MARROW TRANSPLANTATION, 2000, 26 (03) : 257 - 268
  • [40] Clinical research saves money: Reflections on high-dose therapy of breast cancer
    Canellos, GP
    JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (07) : 1965 - 1966
12345