High-dose therapy in breast cancer:: out of favor but not out of promise

被引:5
|
作者
Glück, S [1 ]
Stewart, D [1 ]
机构
[1] Univ Calgary, Tom Baker Canc Ctr, Fac Med, Dept Oncol Med & Pharmacol & Therapeut, Calgary, AB T2N 4N2, Canada
关键词
high-dose chemotherapy; breast cancer; evidence for efficacy; controversy;
D O I
10.1038/sj.bmt.1702388
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The evidence for use of high-dose chemotherapy and autologous stem cell transplantation for breast cancer still remains inconclusive at best, A number of prospective randomized phase III studies have been either published or presented recently or are underway in North America and Europe. It will be crucial to complete the available prospective randomized phase III study and obtain the data when all studies reach a mature status. Only then will level I evidence become available to determine the efficacy and effectiveness of high-dose chemotherapy and autologous stem cell transplantation in breast cancer.
引用
收藏
页码:1017 / 1019
页数:3
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