ONE-POT SYNTHESIS OF 1,8-DIOXO-DECAHYDROACRIDINE DERIVATIVES BY USING NANO-Fe2O3 AS A HIGHLY EFFICIENT AND REUSABLE HETEROGENEOUS CATALYST UNDER SOLVENT-FREE CONDITIONS

被引：0

作者：

Hatamjafari, Farhad ^{[1
]}

Lazarjani, Omid Hosseinnezhad ^{[1
]}

机构：

[1] Islamic Azad Univ, Tonekabon Branch, Fac Sci, Dept Chem, POB 46841-61167, Tonekabon, Iran

来源：

REVUE ROUMAINE DE CHIMIE | 2017年 / 62卷 / 03期

关键词：

1,8-dioxo-decahydroacridines; nano-Fe2O3; multicomponent reactions (MCRs); solvent-free; one-pot; GREEN; NANOPARTICLES; ACRIDINE; 1,8-DIOXO-OCTAHYDROXANTHENES;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and convenient one-step method for synthesis of 1,8-dioxo-decahydroacridines via a multi-component reaction of dimedone, aromatic aldehydes and ammonium acetate catalyzed by nano-Fe2O3 as a catalyst was investigated. The structural features of the synthesized compounds were characterized by melting point, IR and 'H-NMR analysis. The reported catalyst is one-pot, cheap, reusable and safe to handle. The advantages of this protocol are: eco-friendly procedure, mild reaction conditions, excellent yields, operational simplicity and ecofriendly preparation of catalyst.

引用

页码：255 / 260

页数：6

共 44 条

[1] Efficient and Convenient Synthesis of 1,8-Dioxodecahydroacridine Derivatives Using Cu-Doped ZnO Nanocrystalline Powder as a Catalyst under Solvent-Free Conditions
Alinezhad, Heshmatollah
Tavakkoli, Sahar Mohseni
[J]. SCIENTIFIC WORLD JOURNAL, 2013,
[2] [Anonymous], 2014, CHEM SCI T
[3] 2,3-dihydro-1H,7H-pyrimido[5,6,1-de]acridine-1,3,7-trione derivatives, a class of cytotoxic agents active on multidrug-resistant cell lines:: Synthesis, biological evaluation, and structure-activity relationships
Antonini, I
Polucci, P
Kelland, LR
Menta, E
Pescalli, N
Martelli, S
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (14) : 2535 - 2541
[4] Four component and solvent-free synthesis of some new spiro-1,4-dihydropyridines on solid support montmorillonite K10
Azizian, Javad
Hatamjafari, Farhad
Karimi, Ali Reza
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2006, 43 (05) : 1349 - 1352
[5] One-pot Synthesis of 1,8-Dioxo-decahydroacridine Derivatives in Aqueous Media
Balalaie, Saeed
Chadegani, Fatemeh
Darviche, Fatemeh
Bijanzadeh, Hamid Reza
[J]. CHINESE JOURNAL OF CHEMISTRY, 2009, 27 (10) : 1953 - 1956
[6] Vasorelaxing properties of some phenylacridine type potassium channel openers in isolated rabbit thoracic arteries
Berkan, Ö
Saraç, B
Simsek, R
Yildirim, S
Sarioglu, Y
Safak, C
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2002, 37 (06) : 519 - 523
[7] BIDRAM A, 2013, ORIENT J CHEM, V29, P123
[8] Ultrasound assisted multicomponent reactions: A green method for the synthesis of N-substituted 1,8-dioxo-decahydroacridines using β-cyclodextrin as a supramolecular reusable catalyst in water
Chate, Asha V.
Rathod, Umesh B.
Kshirsagar, Jagdish S.
Gaikwad, Pradip A.
Mane, Kishor D.
Mahajan, Pravin S.
Nikam, Mukesh D.
Gill, Charansingh H.
[J]. CHINESE JOURNAL OF CATALYSIS, 2016, 37 (01) : 146 - 152
[9] Amberlyst-15: An efficient reusable heterogeneous catalyst for the synthesis of 1,8-dioxo-octahydroxanthenes and 1,8-dioxo-decahydroacridines
Das, B
Thirupathi, P
Mahender, I
Reddy, VS
Rao, YK
[J]. JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2006, 247 (1-2) : 233 - 239
[10] Synthesis of aza mono, bi and tricyclic compounds.: Evaluation of their anti MDR activity
Gallo, S
Atifi, S
Mahamoud, A
Santelli-Rouvier, C
Wolfárt, K
Molnar, J
Barbe, J
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2003, 38 (01) : 19 - 26

← 1 2 3 4 5 →