Strand Breaks in DNA Samples Induced with LASERIX

被引：0

作者：

Zielbauer, B. ^{[1
]}

Habib, J. ^{[1
]}

Kazamias, S. ^{[1
]}

Guilbaud, O. ^{[1
]}

Pittman, M. ^{[1
]}

Ros, D. ^{[1
]}

du Penhoat, M. -A. Herve ^{[2
]}

Touati, A. ^{[2
]}

Le Sech, C. ^{[3
]}

Porcel, E. ^{[3
]}

Lacombe, S. ^{[3
]}

机构：

[1] Univ Paris 11, CNRS, LIXAM, LASERIX, F-91405 Orsay, France

[2] Univ Paris 06, Inst Minealogie & Phys Milieux Condenses, Paris, France

[3] Univ Paris Sud 11, CNRS, LCAM, Orsay, France

来源：

X-RAY LASERS 2008, PROCEEDINGS | 2009年 / 130卷

关键词：

D O I：

暂无

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Samples of plasmid DNA were irradiated with pulsed 18.9 nm radiation originating from a Mo X-ray laser pumped in GRIP configuration at the LASERIX facility [1]. Surface doses of up to 500 kGray were delivered with a repetition rate of 10 Hz and average pulse energy of 200 nJ. The occurrence of single and double strand breaks not present in controls having undergone the same treatment except for the XRL irradiation can be seen as a clear effect of the XRL irradiation. This confirms the role of direct effects in DNA damages as previously seen with low energy ions [2, 3] and electrons.

引用

页码：409 / +

页数：2

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