Optimal Cutoff Titers for Indirect Immunofluorescence Assay for Diagnosis of Scrub Typhus

被引：41

作者：

Lim, Cherry ^{[1
]}

Blacksell, Stuart D. ^{[1
,2
]}

Laongnualpanich, Achara ^{[3
]}

Kantipong, Pacharee ^{[3
]}

Day, Nicholas P. J. ^{[1
,2
]}

Paris, Daniel H. ^{[1
,2
]}

Limmathurotsakul, Direk ^{[1
,4
]}

机构：

[1] Mahidol Univ, Fac Trop Med, Mahidol Oxford Trop Med Res Unit, Bangkok, Thailand

[2] Univ Oxford, Nuffield Dept Clin Med, Ctr Trop Med & Global Hlth, Oxford, England

[3] Chiang Rai Prachanukroh Hosp, Chiang Rai, Thailand

[4] Mahidol Univ, Fac Trop Med, Dept Trop Hyg, Bangkok, Thailand

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2015年 / 53卷 / 11期

基金：

英国惠康基金;

关键词：

ORIENTIA-TSUTSUGAMUSHI; PCR ASSAY; ACCURACY; ANTIBODY; LEPTOSPIROSIS; INFECTION; TESTS; GOLD;

D O I：

10.1128/JCM.01680-15

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We determined the optimal cutoff titers in admission and convalescent-phase samples for scrub typhus indirect immunofluorescence assay using Bayesian latent class models. Cutoff titers of >= 1:3,200 in an admission sample or of a >= 4-fold rise to >= 1: 3,200 in a convalescent-phase sample provided the highest accuracy (sensitivity, 81.6%; specificity, 100%).

引用

页码：3663 / 3666

页数：4

共 12 条

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