Cyanide Ion-Promoted Nucleophilic Displacement of Aromatic Nitro Groups: A Mild, One-Pot, Transition Metal-Free Synthesis of Nitrile-Containing Naphthalimide Aryl Ether Derivatives

被引：3

作者：

Chen, Lu ^{[1
]}

Chen, Xi ^{[1
]}

Zhu, Tingting ^{[1
]}

Shao, Haibing ^{[1
]}

Chen, Zhihua ^{[1
]}

Hu, Yan ^{[1
]}

Liu, Zhenjiang ^{[1
]}

Liu, Chuanxiang ^{[1
]}

机构：

[1] Shanghai Inst Technol, Sch Chem & Environm Engn, Shanghai 201418, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 86卷 / 03期

基金：

上海市自然科学基金;

关键词：

31;

D O I：

10.1021/acs.joc.0c02598

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Herein we report the novel synthesis of nitrile-containing naphthalimide aryl ether derivatives via transition metal-free cyanide ion-promoted nucleophilic displacement of nitronaphthalimide with alcohols or phenols. The transformation involves a one-pot reaction, which is operationally simple and mild and bereft of transition metal catalysts. This work provides a novel route for the preparation of diary! ether derivatives.

引用

页码：3059 / 3064

页数：6

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