CAR-T treatment of pediatric AML: a long and winding road

被引：8
|
作者：
De Moerloose, Barbara [1 ]
机构：
[1] Ghent Univ Hosp, Ghent, Belgium
来源：
BLOOD | 2021年 / 137卷 / 08期
关键词：
D O I：
10.1182/blood.2020009406
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this issue of Blood, Willier et al explored the differences in immunotarget expression in pediatric (ped) acute myeloid leukemia (AML) compared with adult AML. They identified CD33 and CLEC12A (CLL1) as the best combination for immunotherapy in ped AML. Their findings underscore the need to delineate immunotarget expression levels prior to (pre-)clinical application of chimeric antigen receptor (CAR)-T-cell treatment.(1)
引用
收藏
页码：1004 / 1006
页数：4
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