SYNTHESIS AND CHARACTERIZATION OF NOVEL PYRIMIDINE DERIVATIVES FROM 2,3-FURANDIONES

被引：4

作者：

Koca, Irfan ^{[1
]}

Yildirim, Ismail ^{[2
]}

机构：

[1] Bozok Univ, Fac Arts & Sci, Dept Chem, TR-66200 Yozgat, Turkey

[2] Erciyes Univ, Fac Arts & Sci, Dept Chem, TR-38039 Kayseri, Turkey

来源：

HETEROCYCLIC COMMUNICATIONS | 2009年 / 15卷 / 05期

关键词：

2,3-Furandione; pyrimidine-2(1H)-one; pyrimidine-2(1-H)-thione; nucleophilic cycloaddition; FUNCTIONALIZED; 1H-PYRIMIDINES; OXALYL COMPOUNDS; ENAMINONES; INHIBITORS; AGENTS; ACID;

D O I：

10.1515/HC.2009.15.5.377

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various novel pyrimidine-2(1H)-one and pyrimidine-2(1H)-thione derivatives 3a-m have been synthesized efficiently in good yields by the treatment of 4-p-methylbenzoyl-5-p-methylphenyl-2,3-furandione (1a) and 4-(3,4-dimethoxybenzoyl)-5-(3,4-dimethoxyphenyl)-2,3-furandione (1b) with some ureas and thioureas 2. Structures of these compounds 3 were established on the basis of elemental analysis, IR, H-1- and C-13-NMR spectral studies.

引用

页码：377 / 384

页数：8

共 50 条

[41] Synthesis of 2,4-Diaminoquinazoline and 2,4-Diaminopyrido-[2,3-d]pyrimidine Derivatives
Deng, Lanqing
Zhong, Hong
Wang, Shuai
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2014, 34 (02) : 414 - 418
[42] Synthesis of Novel Tetra-Substituted Pyrazole Derivatives from 2,3-Furandione
Genc, Hasan
Tasdemir, Volkan
Tozlu, Israfil
Ogun, Erdal
LETTERS IN ORGANIC CHEMISTRY, 2019, 16 (11) : 891 - 897
[43] Facile Synthesis of Thieno[2,3-d]pyrimidine Derivatives Using Inorganic Base Catalysis
Meng, Shuangming
Jia, Zhifang
Wang, Kewei
Fan, Yueqin
Guo, Yong
SYNTHETIC COMMUNICATIONS, 2014, 44 (10) : 1461 - 1465
[44] SYNTHESIS OF NEW PYRROLE AND PYRROLO[ 2,3-d]PYRIMIDINE DERIVATIVES OF POTENTIAL ANTIOXIDANT ACTIVITY
El-Bayouki, Khairy Abdelhameed Mohsen
Basyouni, Wahid Mohmoud
Mostafa, Eslam Attya
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 2010, 75 (08) : 813 - 834
[45] Synthesis and anticancer activities of diverse furo[2,3-d]pyrimidine and benzofuro[3,2-d]pyrimidine derivatives
Tang, Xiaoyu
Zheng, Aihua
Wu, Fengxu
Liao, Chujie
Hu, Yanggen
Luo, Chao
SYNTHETIC COMMUNICATIONS, 2022, 52 (07) : 994 - 1003
[46] Microwave assisted synthesis of novel pyrimidine derivatives and investigation of their analgesic and ulcerogenic activity
Chaudhary, Anshu
Sharma, Pramod Kumar
Verma, Prabhakar
Kumar, Nitin
Dudhe, Rupesh
MEDICINAL CHEMISTRY RESEARCH, 2012, 21 (11) : 3629 - 3645
[47] Glucose-Decorated Silica-Molybdate Complex: A Novel Catalyst for Facile Synthesis of Pyrano [2,3-d] -Pyrimidine Derivatives
Pourkazemi, Arezoo
Asaadi, Negin
Farahi, Mahnaz
Zarnegaryan, Ali
Karami, Bahador
ACTA CHIMICA SLOVENICA, 2022, 69 (01) : 30 - 38
[48] Cycloaddition of Aroyl Isothiocyanate: A Novel Synthesis of Triazine, Oxazine, Pyrimidine, and Pyridine Derivatives
Assy, Mohamed G.
El-Sayed, Hassan A.
Ouf, Nabil H.
Hamza, Ahmed
Morsy, Hesham A.
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 56 (10) : 2954 - 2959
[49] Synthesis and Biological Evaluation of Some Novel Thieno[2,3-d] pyrimidine Derivatives as Potential Anti-inflammatory and Analgesic Agents
El-Tombary, Alaa A.
El-Hawash, Soad A. M.
Habib, Nargues S.
Soliman, Raafat
El-Ashmawy, Ibrahim M.
Shaaban, Omaima G.
MEDICINAL CHEMISTRY, 2013, 9 (08) : 1099 - 1112
[50] Synthesis, Characterization, Biological Activity of Novel 1H-benzo[f]chromene and 12H-benzo[f] chromeno[2,3-d] pyrimidine Derivatives
Abd El-Mawgoud, Heba K.
Radwan, Hebat Allah M.
El-Mariah, Fatma
El-Agrody, Ahmed M.
LETTERS IN DRUG DESIGN & DISCOVERY, 2018, 15 (08) : 857 - 865

← 1 2 3 4 5 →