Optimisation of contribution of candidate parents to maximise genetic gain and restricting inbreeding using semidefinite programming - (Open Access publication)

被引:38
作者
Pong-Wong, Ricardo [1 ]
Woolliams, John A. [1 ]
机构
[1] Roslin Inst, Roslin EH25 9PS, Midlothian, Scotland
基金
英国生物技术与生命科学研究理事会;
关键词
inbreeding restriction; optimisation of contributions; semidefinite-programming;
D O I
10.1051/gse:2006031
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
An approach for optimising genetic contributions of candidates to control inbreeding in the offspring generation using semidefinite programming (SDP) was proposed. Formulations were done for maximising genetic gain while restricting inbreeding to a preset value and for minimising inbreeding without regard of gain. Adaptations to account for candidates with fixed contributions were also shown. Using small but traceable numerical examples, the SDP method was compared with an alternative based upon Lagrangian multipliers (RSRO). The SDP method always found the optimum solution that maximises genetic gain at any level of restriction imposed on inbreeding, unlike RSRO which failed to do so in several situations. For these situations, the expected gains from the solution obtained with RSRO were between 1.5-9% lower than those expected from the optimum solution found with SDP with assigned contributions varying widely. In conclusion SDP is a reliable and flexible method for solving contribution problems.
引用
收藏
页码:3 / 25
页数:23
相关论文
共 28 条
[1]   Primal-dual interior-point methods for semidefinite programming: Convergence rates, stability and numerical results [J].
Alizadeh, F ;
Haeberly, JPA ;
Overton, ML .
SIAM JOURNAL ON OPTIMIZATION, 1998, 8 (03) :746-768
[2]  
[Anonymous], STUDIES APPL MATH
[3]  
BELONSKY GM, 1988, J ANIM SCI, V66, P1124
[4]  
BENSON SJ, 2005, DSDP5 SOFTWARE SEMID
[5]   CSDP, a C library for semidefinite programming [J].
Borchers, B .
OPTIMIZATION METHODS & SOFTWARE, 1999, 11-2 (1-4) :613-623
[6]  
BOYD S, 2005, CONVEX PROGRAMMING
[7]   BALANCING SELECTION RESPONSE AND RATE OF INBREEDING BY INCLUDING GENETIC-RELATIONSHIPS IN SELECTION DECISIONS [J].
BRISBANE, JR ;
GIBSON, JP .
THEORETICAL AND APPLIED GENETICS, 1995, 91 (03) :421-431
[8]   A method for the dynamic management of genetic variability in dairy cattle [J].
Colleau, JJ ;
Moureaux, S ;
Briend, M ;
Bechu, J .
GENETICS SELECTION EVOLUTION, 2004, 36 (04) :373-394
[9]   Optimizing selection for quantitative traits with information on an identified locus in outbred populations [J].
Dekkers, JCM ;
van Arendonk, JAM .
GENETICS RESEARCH, 1998, 71 (03) :257-275
[10]   MARKER ASSISTED SELECTION USING BEST LINEAR UNBIASED PREDICTION [J].
FERNANDO, RL ;
GROSSMAN, M .
GENETICS SELECTION EVOLUTION, 1989, 21 (04) :467-477