Verrucoid lesions of mitral valve in a dog with features of inflammatory myofibroblastic tumor

被引：6

作者：

Tursi, Massimiliano ^{[1
]}

Garofalo, Luca ^{[2
]}

Muscio, Maruska ^{[2
]}

Galloni, Marco ^{[3
]}

Zanatta, Renato ^{[1
]}

Borgarelli, Michele ^{[1
]}

Pucci, Angela ^{[2
]}

机构：

[1] Univ Turin, Sch Vet, Dept Anim Pathol, I-10124 Turin, Italy

[2] ASO OIRM S Anna, Regina Margherita Hosp, Dept Histopathol, Turin, Italy

[3] Univ Turin, Sch Vet, Dept Vet Morphophysiol, I-10124 Turin, Italy

来源：

CARDIOVASCULAR PATHOLOGY | 2009年 / 18卷 / 05期

关键词：

Dog; Mitral valve; Cardiac tumor; Inflammatory myofibroblastic tumor; OF-THE-LITERATURE; PSEUDOTUMOR;

D O I：

10.1016/j.carpath.2007.12.017

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a mitral valve lesion detected at autopsy in a 9-year-old male German Shepherd dog suffering from mild mitral regurgitation. Gross examination of the heart showed exophitic, noncontiguous lesions involving the atrial aspect of both mitral leaflets. Microscopic evaluation of the mitral lesions disclosed a diffuse proliferation of myofibroblasts with little atypia, arranged loosely and rather randomly, within a myxoid stroma and associated with inflammatory cells identified as CD138+ plasma cells, CD68+ macrophages, and eosinophils. The myofibroblastic proliferation we describe is quite similar to previously described inflammatory myofibroblastic tumor (IMT), a very rare lesion, exceptionally found in the human heart. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：315 / 316

页数：2

共 4 条

[1] Cardiac inflammatory myofibroblastic tumor: A "benign" neoplasm that may result in syncope, myocardial infarction, and sudden death [J].

Burke, Allen ;

Li, Ling ;

Kling, Elaine ;

Kutys, Robert ;

Virmani, Renu ;

Miettinen, Markku .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2007, 31 (07) :1115-1122

[2] Inflammatory myofibroblastic tumor with valvular involvement: a case report and review of the literature [J].

Butany, Jagdish ;

Dixit, Vidya ;

Leong, Shaun W. ;

Daniel, Lorretta B. ;

Mezody, Mellita ;

David, Tirone E. .

CARDIOVASCULAR PATHOLOGY, 2007, 16 (06) :359-364

[3] Inflammatory pseudotumour of the spleen in a dog [J].

Gärtner, F ;

Santos, M ;

Gillette, D ;

Schmitt, F .

VETERINARY RECORD, 2002, 150 (22) :697-698

[4] Inflammatory pseudotumor of the liver associated with malignant disease: report of two cases and a review of the literature [J].

Nishimura, R ;

Teramoto, N ;

Tanada, M ;

Kurita, A ;

Mogami, H .

VIRCHOWS ARCHIV, 2005, 447 (03) :660-664

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