Clostridium difficile Infection in Liver Cirrhosis Carries a Higher Risk of Mortality: A Comprehensive Literature Review

被引：8

作者：

Aravamudan, Veeraraghavan Meyyur ^{[1
]}

Khan, Shahab R. ^{[2
]}

Hussain, Ikram ^{[3
]}

机构：

[1] Woodlands Hlth Campus, Internal Med, Singapore, Singapore

[2] Univ Arizona, Banner Univ Med Ctr Tucson, Internal Med, Tucson, AZ USA

[3] Woodlands Hlth Campus, Internal Med Gastroenterol, Singapore, Singapore

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2019年 / 11卷 / 08期

关键词：

clostridium difficile infection; cirrhosis; mortality;

D O I：

10.7759/cureus.5463

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Clostridium difficile (C. difficile) infection is associated with higher mortality in liver cirrhosis. This literature review discusses the risk factors associated with increased mortality in patients with C. difficile infection in liver cirrhosis. This literature review also highlights the importance of selecting antibiotics wisely, carefully selecting patients who are candidates for antibiotic prophylaxis for spontaneous bacterial peritonitis in liver cirrhosis and avoiding unnecessary proton pump inhibitors in liver cirrhosis.

引用

页数：7

共 13 条

[1] Clostridium difficile infection in hospitalized liver transplant patients: A nationwide analysis [J].

Ali, Muhammad ;

Ananthakrishnan, Ashwin N. ;

Ahmad, Shahryar ;

Kumar, Nilay ;

Kumar, Gagan ;

Saeian, Kia .

LIVER TRANSPLANTATION, 2012, 18 (08) :972-978

[2] Second Infections Independently Increase Mortality in Hospitalized Patients With Cirrhosis: The North American Consortium for the Study of End-Stage Liver Disease (NACSELD) Experience [J].

Bajaj, Jasmohan S. ;

O'Leary, Jacqueline G. ;

Reddy, K. Rajender ;

Wong, Florence ;

Olson, Jody C. ;

Subramanian, Ram M. ;

Brown, Geri ;

Noble, Nicole A. ;

Thacker, Leroy R. ;

Kamath, Patrick S. .

HEPATOLOGY, 2012, 56 (06) :2328-2335

[3] Clostridium difficile Is Associated With Poor Outcomes in Patients With Cirrhosis: A National and Tertiary Center Perspective [J].

Bajaj, Jasmohan S. ;

Ananthakrishnan, Ashwin N. ;

Hafeezullah, Muhammad ;

Zadvornova, Yelena ;

Dye, Alexis ;

McGinley, Emily L. ;

Saeian, Kia ;

Heuman, Douglas ;

Sanyal, Arun J. ;

Hoffmann, Raymond G. .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 (01) :106-113

[4] Trends in mortality following Clostridium difficile infection in Scotland, 2010-2016: a retrospective cohort and case-control study [J].

Banks, A. ;

Moore, E. K. ;

Bishop, J. ;

Coia, J. E. ;

Brown, D. ;

Mather, H. ;

Wiuff, C. .

JOURNAL OF HOSPITAL INFECTION, 2018, 100 (02) :133-141

[5]

Dotson KM, 2018, EPIDEMIOL INFECT, V146, P1101, DOI [10.1017/s0950268818001036, 10.1017/S0950268818001036]

[6] MELD is the only predictor of short-term mortality in cirrhotic patients with C. difficile infection [J].

Hong, Simon J. ;

Feuerstadt, Paul ;

Brandt, Lawrence J. .

DIGESTIVE AND LIVER DISEASE, 2019, 51 (02) :275-280

[7]

Kruger AJ, 2018, GASTROENTEROLOGY, V154, pS271

[8] Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003:: a changing pattern of disease severity [J].

Pépin, J ;

Valiquette, L ;

Alary, ME ;

Villemure, P ;

Pelletier, A ;

Forget, K ;

Pépin, K ;

Chouinard, D .

CANADIAN MEDICAL ASSOCIATION JOURNAL, 2004, 171 (05) :466-472

[9] The rise of Clostridioides difficile infections and fall of associated mortality in hospitalized advanced cirrhotics [J].

Rosenblatt, Russell ;

Mehta, Amit ;

Cohen-Mekelburg, Shirley ;

Shen, Nicole ;

Snell, David ;

Lucero, Catherine ;

Jesudian, Arun ;

Fortune, Brett ;

Crawford, Carl V. ;

Kumar, Sonal .

LIVER INTERNATIONAL, 2019, 39 (07) :1263-1270

[10] Hospitalized Patients with Cirrhosis Should Be Screened for Clostridium difficile Colitis [J].

Saab, Sammy ;

Alper, Theodore ;

Sernas, Ernesto ;

Pruthi, Paridhima ;

Alper, Mikhail A. ;

Sundaram, Vinay .

DIGESTIVE DISEASES AND SCIENCES, 2015, 60 (10) :3124-3129

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