Poly (ADP-Ribose) Polymerase Inhibitor Activity in Prostate Cancers Harboring Mutations in DNA Repair Genes: Who Benefits?

被引:5
作者
Ganesan, Shridar [1 ]
Garber, Judy [2 ]
机构
[1] Rutgers Canc Inst New Jersey, 195 Little Albany St, New Brunswick, NJ 08903 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
关键词
BRCA1;
D O I
10.1200/PO.20.00269
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1034 / 1037
页数:4
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共 25 条
[1]   Significant Tumor Response to the Poly (ADP-ribose) Polymerase Inhibitor Olaparib in Heavily Pretreated Patient With Ovarian Carcinosarcoma Harboring a Germline RAD51D Mutation [J].
Chandran, Elias A. ;
Kennedy, Ian .
JCO PRECISION ONCOLOGY, 2018, 2 :1-4
[2]   Biomarker-Guided Development of DNA Repair Inhibitors [J].
Cleary, James M. ;
Aguirre, Andrew J. ;
Shapiro, Geoffrey I. ;
D'Andrea, Alan D. .
MOLECULAR CELL, 2020, 78 (06) :1070-1085
[3]   HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures [J].
Davies, Helen ;
Glodzik, Dominik ;
Morganella, Sandro ;
Yates, Lucy R. ;
Staaf, Johan ;
Zou, Xueqing ;
Ramakrishna, Manasa ;
Martin, Sancha ;
Boyault, Sandrine ;
Sieuwerts, Anieta M. ;
Simpson, Peter T. ;
King, Tari A. ;
Raine, Keiran ;
Eyfjord, Jorunn E. ;
Kong, Gu ;
Borg, Ake ;
Birney, Ewan ;
Stunnenberg, Hendrik G. ;
van de Vijver, Marc J. ;
Borresen-Dale, Anne-Lise ;
Martens, John W. M. ;
Span, Paul N. ;
Lakhani, Sunil R. ;
Vincent-Salomon, Anne ;
Sotiriou, Christos ;
Tutt, Andrew ;
Thompson, Alastair M. ;
Van Laere, Steven ;
Richardson, Andrea L. ;
Viari, Alain ;
Campbell, Peter J. ;
Stratton, Michael R. ;
Nik-Zainal, Serena .
NATURE MEDICINE, 2017, 23 (04) :517-+
[4]   Olaparib for Metastatic Castration-Resistant Prostate Cancer [J].
de Bono, J. ;
Mateo, J. ;
Fizazi, K. ;
Saad, F. ;
Shore, N. ;
Sandhu, S. ;
Chi, K. N. ;
Sartor, O. ;
Agarwal, N. ;
Olmos, D. ;
Thiery-Vuillemin, A. ;
Twardowski, P. ;
Mehra, N. ;
Goessl, C. ;
Kang, J. ;
Burgents, J. ;
Wu, W. ;
Kohlmann, A. ;
Adelman, C. A. ;
Hussain, M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (22) :2091-2102
[5]   Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers. [J].
Fong, Peter C. ;
Boss, David S. ;
Yap, Timothy A. ;
Tutt, Andrew ;
Wu, Peijun ;
Mergui-Roelvink, Marja ;
Mortimer, Peter ;
Swaisland, Helen ;
Lau, Alan ;
O'Connor, Mark J. ;
Ashworth, Alan ;
Carmichael, James ;
Kaye, Stan B. ;
Schellens, Jan H. M. ;
de Bono, Johann S. .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (02) :123-134
[6]   Tumor Suppressor Tolerance: Reversion Mutations in BRCA1 and BRCA2 and Resistance to PARP Inhibitors and Platinum [J].
Ganesan, Shridar .
JCO PRECISION ONCOLOGY, 2018, 2
[7]   Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer [J].
Golan, Talia ;
Hammel, Pascal ;
Reni, Michele ;
Van Cutsem, Eric ;
Macarulla, Teresa ;
Hall, Michael J. ;
Park, Joon-Oh ;
Hochhauser, Daniel ;
Arnold, Dirk ;
Oh, Do-Youn ;
Reinacher-Schick, Anke ;
Tortora, Giampaolo ;
Alguel, Hana ;
O'Reilly, Eileen M. ;
McGuinness, David ;
Cui, Karen Y. ;
Schlienger, Katia ;
Locker, Gershon Y. ;
Kindler, Hedy L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2019, 381 (04) :317-327
[8]   Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer [J].
Gonzalez-Martin, A. ;
Pothuri, B. ;
Vergote, I. ;
DePont Christensen, R. ;
Graybill, W. ;
Mirza, M. R. ;
McCormick, C. ;
Lorusso, D. ;
Hoskins, P. ;
Freyer, G. ;
Baumann, K. ;
Jardon, K. ;
Redondo, A. ;
Moore, R. G. ;
Vulsteke, C. ;
O'Cearbhaill, R. E. ;
Lund, B. ;
Backes, F. ;
Barretina-Ginesta, P. ;
Haggerty, A. F. ;
Rubio-Perez, M. J. ;
Shahin, M. S. ;
Mangili, G. ;
Bradley, W. H. ;
Bruchim, I. ;
Sun, K. ;
Malinowska, I. A. ;
Li, Y. ;
Gupta, D. ;
Monk, B. J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2019, 381 (25) :2391-2402
[9]   Talazoparib beyond BRCA: A phase II trial of talazoparib monotherapy in BRCA1 and BRCA2 wild-type patients with advanced HER2-negative breast cancer or other solid tumors with a mutation in homologous recombination (HR) pathway genes. [J].
Gruber, Joshua James ;
Afghahi, Anosheh ;
Hatton, Alyssa ;
Scott, Danika ;
McMillan, Alex ;
Ford, James M. ;
Telli, Melinda L. .
JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
[10]   Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance [J].
Horak, Peter ;
Weischenfeldt, Joachim ;
von Amsberg, Gunhild ;
Beyer, Burkhard ;
Schuette, Andreas ;
Uhrig, Sebastian ;
Gieldon, Laura ;
Klink, Barbara ;
Feuerbach, Lars ;
Huebschmann, Daniel ;
Kreutzfeldt, Simon ;
Heining, Christoph ;
Maier, Sebastian ;
Hutter, Barbara ;
Penzel, Roland ;
Schlesner, Matthias ;
Eils, Roland ;
Sauter, Guido ;
Stenzinger, Albrecht ;
Brors, Benedikt ;
Schroeck, Evelin ;
Glimm, Hanno ;
Froehling, Stefan ;
Schlomm, Thorsten .
COLD SPRING HARBOR MOLECULAR CASE STUDIES, 2019, 5 (02)