Scavenging effect and antispasmodic activity of the essential oil of Cyclotrichium niveum

被引:22
作者
Cetinus, Senay Akkus [1 ]
Goze, Ismihan
Sarac, Bulent
Vural, Nilufer
机构
[1] Cumhuriyet Univ, Fac Sci & Literature, Dept Chem, TR-58140 Cumhuriyet, Turkey
[2] Cumhuriyet Univ, Sch Med, Dept Pharmacol, TR-58140 Sivas, Turkey
[3] Ankara Univ, Res Ctr, BIATUM, TR-06100 Ankara, Turkey
关键词
Cyclotrichium niveum; antioxidant activity; antispasmodic activity;
D O I
10.1016/j.fitote.2006.10.006
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The radical scavenging and the spasmolitic activity of Cyclotrichium niveum essential oil were evaluated in vitro. It showed an IC50 of 1750 mu g/ml on DPPH method and dose dependently (0.1, 0.5 and 1 mg/ml) inhibits the contraction induced by carbachol on rabbit bladder from 15 to 100%. Moreover, it was able to inhibit the rat ileum muscle by 30 to 100%. (c) 2006 Elsevier B.V All rights reserved.
引用
收藏
页码:129 / 133
页数:5
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