Lupus arthritis

被引:88
作者
Grossman, Jennifer M. [1 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Div Rheumatol, Dept Med, Los Angeles, CA 90095 USA
来源
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY | 2009年 / 23卷 / 04期
关键词
systemic lupus erythematosus; arthritis; AVN; treatment; PLACEBO-CONTROLLED TRIAL; CITRULLINATED PEPTIDE ANTIBODIES; ERYTHEMATOSUS DISEASE-ACTIVITY; RANDOMIZED CONTROLLED-TRIAL; ATLANTO-AXIAL SUBLUXATION; OF-THE-LITERATURE; TENDON-RUPTURE; DOUBLE-BLIND; MYCOPHENOLATE-MOFETIL; DEFORMING ARTHROPATHY;
D O I
10.1016/j.berh.2009.04.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Arthritis in systemic lupus erythematosus (SLE) is one of the most common disease manifestations. Nearly all joints call be affected by SLE, but hand and knee involvement are the most typical. Periarticular structures call be inflamed leading to tendonitis, tenosynovitis and tendon rupture. Avascular necrosis (AVN) also Occurs Causing joint pain and disability, typically ill larger joints such as the hip and knee. This article addresses the clinical features Of arthritis ill lupus and an approach to the differential diagnosis. Treatment strategies include nonsteroidal anti-inflammatories, corticosteroids, anti-malarials and a variety Of immunosuppressive medications. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:495 / 506
页数:12
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