Reduction of CaV channel activities by Ca2+-CaM: inactivation or deactivation?

被引:2
作者
Cui, Jianmin [1 ]
机构
[1] Washington Univ, Arrhythmia Ctr, Dept Biomed Engn & Cardiac Bioelect, St Louis, MO 63130 USA
关键词
VOLTAGE-DEPENDENT INACTIVATION; CALCIUM-CHANNELS; POTASSIUM CHANNELS; CA2+-DEPENDENT INACTIVATION; CRYSTAL-STRUCTURE; CALMODULIN; MECHANISM; CA2+/CALMODULIN; COMPLEX; DOMAIN;
D O I
10.1085/jgp.201010421
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
引用
收藏
页码:297 / 301
页数:5
相关论文
共 34 条
[1]   DESTRUCTION OF SODIUM CONDUCTANCE INACTIVATION IN SQUID AXONS PERFUSED WITH PRONASE [J].
ARMSTRONG, CM ;
BEZANILLA, F ;
ROJAS, E .
JOURNAL OF GENERAL PHYSIOLOGY, 1973, 62 (04) :375-391
[3]   Voltage-gated ion channels and electrical excitability [J].
Armstrong, CM ;
Hille, B .
NEURON, 1998, 20 (03) :371-380
[4]   The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels [J].
Barrett, Curtis F. ;
Tsien, Richard W. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (06) :2157-2162
[5]   INACTIVATION OF SODIUM CHANNEL .1. SODIUM CURRENT EXPERIMENTS [J].
BEZANILLA, F ;
ARMSTRONG, CM .
JOURNAL OF GENERAL PHYSIOLOGY, 1977, 70 (05) :549-566
[6]   Voltage and calcium use the same molecular determinants to inactivate calcium channels [J].
Cens, T ;
Restituito, S ;
Galas, S ;
Charnet, P .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (09) :5483-5490
[7]   Molecular driving forces determining potassium channel slow inactivation [J].
Cordero-Morales, Julio F. ;
Jogini, Vishwanath ;
Lewis, Anthony ;
Vasquez, Valeria ;
Cortes, D. Marien ;
Roux, Benoit ;
Perozo, Eduardo .
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2007, 14 (11) :1062-1069
[8]   Calmodulin bifurcates the local Ca2+ signal that modulates P/Q-type Ca2+ channels [J].
DeMaria, CD ;
Soong, TW ;
Alseikhan, BA ;
Alvania, RS ;
Yue, DT .
NATURE, 2001, 411 (6836) :484-489
[9]   Structure of calmodulin bound to the hydrophobic IQ domain of the cardiac Cav1.2 calcium channel [J].
Fallon, JL ;
Halling, DB ;
Hamilton, SL ;
Quiocho, FA .
STRUCTURE, 2005, 13 (12) :1881-1886
[10]   Disruption of the IS6-AID Linker Affects Voltage-gated Calcium Channel Inactivation and Facilitation [J].
Findeisen, Felix ;
Minor, Daniel L., Jr. .
JOURNAL OF GENERAL PHYSIOLOGY, 2009, 133 (03) :327-343