Chemoenzymatic dynamic kinetic resolution of secondary amines

被引：93

作者：

Stirling, Matthew

Blacker, John

Page, Michael I. ^{[1
]}

机构：

[1] Univ Huddersfield, Dept Chem & Biol Sci, Huddersfield HD1 3DH, W Yorkshire, England

[2] NPILPharma, Huddersfield HD1 9GA, W Yorkshire, England

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 07期

关键词：

D O I：

10.1016/j.tetlet.2006.12.032

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：1247 / 1250

页数：4

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