Rise of sodium-glucose cotransporter 2 inhibitors in the management of nonalcoholic fatty liver disease

被引：7
作者：
Dokmak, Amr [1 ,2 ]
Almeqdadi, Mohammad [1 ,2 ]
Trivedi, Hirsh [3 ]
Krishnan, Sandeep [2 ,4 ]
机构：
[1] St Elizabeths Med Ctr, Div Med, Brighton, MA 02135 USA
[2] Tufts Univ, Sch Med, Boston, MA 02111 USA
[3] Beth Israel Deaconess Med Ctr, Div Gastroenterol, Boston, MA 02215 USA
[4] St Elizabeths Med Ctr, Div Gastroenterol, 736 Cambridge St, Brighton, MA 02135 USA
来源：
WORLD JOURNAL OF HEPATOLOGY | 2019年 / 11卷 / 07期
关键词：
Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Sodium-glucose cotransporter 2 inhibitors; Liver cirrhosis; Diabetes; TYPE-2; DIABETES-MELLITUS; INSULIN-RESISTANCE; HEPATIC STEATOSIS; ALANINE AMINOTRANSFERASE; CARDIOVASCULAR-DISEASE; METABOLIC SIGNIFICANCE; NATURAL-HISTORY; VITAMIN-E; DAPAGLIFLOZIN; PREVALENCE;
D O I：
10.4254/wjh.v11.i7.562
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in the Western world. It is more prevalent in male gender, and with increasing age, obesity, and insulin resistance. Besides weight loss, there are limited treatment options. The use of anti-diabetic medications has been studied with mixed results. In this review, we discuss the use of anti-diabetic medications in the management of NAFLD with a specific focus on sodium-glucose cotransporter 2 inhibitors. We shed light on the evidence supporting their use in detail and discuss limitations and future directions.
引用
收藏
页码：562 / 573
页数：12
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