Marine mammals harbor unique microbiotas shaped by and yet distinct from the sea

被引：182

作者：

Bik, Elisabeth M. ^{[1
,2
]}

Costello, Elizabeth K. ^{[1
]}

Switzer, Alexandra D. ^{[1
]}

Callahan, Benjamin J. ^{[3
]}

Holmes, Susan P. ^{[3
]}

Wells, Randall S. ^{[4
]}

Carlin, Kevin P. ^{[5
]}

Jensen, Eric D. ^{[6
]}

Venn-Watson, Stephanie ^{[5
]}

Relman, David A. ^{[1
,2
,7
]}

机构：

[1] Stanford Univ, Sch Med, Dept Microbiol & Immunol, Stanford, CA 94305 USA

[2] Vet Affairs Palo Alto Hlth Care Syst, Palo Alto, CA 94304 USA

[3] Stanford Univ, Dept Stat, Stanford, CA 94305 USA

[4] Mote Marine Lab, Chicago Zool Soc, Sarasota Dolphin Res Program, Sarasota, FL 34236 USA

[5] Natl Marine Mammal Fdn, Translat Med & Res Program, San Diego, CA 92106 USA

[6] Space & Naval Warfare Syst Ctr Pacific, San Diego, CA 92152 USA

[7] Stanford Univ, Sch Med, Dept Med Infect Dis & Geog Med, Stanford, CA 94305 USA

来源：

NATURE COMMUNICATIONS | 2016年 / 7卷

关键词：

BOTTLE-NOSED DOLPHINS; SEGMENTED FILAMENTOUS BACTERIA; RNA GENE DATABASE; TURSIOPS-TRUNCATUS; GUT MICROBIOME; SP-NOV; DIVERSITY; EVOLUTION; MICROORGANISMS; CONVERGENCE;

D O I：

10.1038/ncomms10516

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Marine mammals play crucial ecological roles in the oceans, but little is known about their microbiotas. Here we study the bacterial communities in 337 samples from 5 body sites in 48 healthy dolphins and 18 healthy sea lions, as well as those of adjacent seawater and other hosts. The bacterial taxonomic compositions are distinct from those of other mammals, dietary fish and seawater, are highly diverse and vary according to body site and host species. Dolphins harbour 30 bacterial phyla, with 25 of them in the mouth, several abundant but poorly characterized Tenericutes species in gastric fluid and a surprisingly paucity of Bacteroidetes in distal gut. About 70% of near-full length bacterial 16S ribosomal RNA sequences from dolphins are unique. Host habitat, diet and phylogeny all contribute to variation in marine mammal distal gut microbiota composition. Our findings help elucidate the factors structuring marine mammal microbiotas and may enhance monitoring of marine mammal health.

引用

页数：13

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