A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19

被引：13

作者：

Remppis, Jonathan ^{[1
]}

Ganzenmueller, Tina ^{[2
]}

Vasconcelos, Malte Kohns ^{[3
]}

Heinzel, Oliver ^{[1
]}

Handgretinger, Rupert ^{[1
]}

Renk, Hanna ^{[1
]}

机构：

[1] Univ Childrens Hosp Tuebingen, Dept Haematol & Oncol, Hoppe Seyler Str 1, D-72076 Tubingen, Germany

[2] Univ Hosp Tuebingen, Inst Med Virol, Elfriede Aulhorn Str 6, D-72076 Tubingen, Germany

[3] Heinrich Heine Univ Dusseldorf, Inst Med Microbiol & Hosp Hyg, Dusseldorf, Germany

来源：

BMC INFECTIOUS DISEASES | 2021年 / 21卷 / 01期

关键词：

COVID-19; SARS CoV-2 infection; Children; Comorbidity; Inpatients;

D O I：

10.1186/s12879-021-05791-8

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

BackgroundWhile our knowledge about COVID-19 in adults has rapidly increased, data on the course of disease and outcome in children with different comorbidities is still limited.MethodsProspective, observational study at a tertiary care children's hospital in southern Germany. Clinical and virology data from all paediatric patients admitted with SARS-CoV-2 infection at our hospital were prospectively assessed.ResultsBetween March and November 2020, 14 patients were admitted with COVID-19. One patient was admitted a second time with COVID-19 6 months after initial disease. Among seven patients with severe underlying comorbidities, three developed multisystem inflammatory syndrome (MIS-C), two were admitted to the paediatric intensive care unit. One patient needed invasive ventilation. Another patient died shortly after discharge of COVID-19-related complications.ConclusionsWhile COVID-19 generally causes mild disease in children, severe respiratory illness and MIS-C occur, in some cases with fatal outcome. Children with underlying diseases might be at special risk for severe disease.

引用

页数：6

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