Dyslipidemia involvement in the development of polycystic ovary syndrome

被引：84

作者：

Liu, Qi ^{[1
]}

Xie, Yuan-jie ^{[1
]}

Qu, Li-hua ^{[1
]}

Zhang, Meng-xia ^{[1
,2
]}

Mo, Zhong-cheng ^{[1
]}

机构：

[1] Univ South China, Clin Anat & Reprod Med Applicat Inst, Dept Histol & Embryol, Hengyang 421001, Hunan, Peoples R China

[2] Humanitas Univ Chinese Med, Dept Histol & Embryol, Changsha 410208, Hunan, Peoples R China

来源：

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY | 2019年 / 58卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Polycystic ovary syndrome; Lipid; Hyperandrogenism; Insulin resistance; Lipid-lowering drugs; CARDIOVASCULAR RISK-FACTORS; VISCERAL ADIPOSITY INDEX; HIGH-DENSITY-LIPOPROTEIN; REACTIVE PROTEIN-LEVELS; INSULIN-RESISTANCE; METABOLIC-DISORDERS; OXIDATIVE STRESS; INFERTILE WOMEN; GRANULOSA-CELLS; OMEGA-3-FATTY-ACIDS SUPPLEMENTATION;

D O I：

10.1016/j.tjog.2019.05.003

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Polycystic ovary syndrome (PCOS) is widely accepted as the most common endocrine abnormality in women of childbearing age and may be accompanied by dyslipidemia, hyperandrogenism, hyperinsulinemia, oxidative stress and infertility. Dyslipidemia is now known to play an important role in the development of PCOS. Lipid abnormalities, including elevated low-density lipoprotein and triglyceride levels and reduced high-density lipoprotein levels, are often found in women with PCOS and play an important role in PCOS; therefore, we summarize the effect of lipid abnormalities on hyperandrogenism, insulin resistance, oxidative stress and infertility in PCOS and review the effects of common lipid-lowering drugs on patients with PCOS. The purpose of this article is to elucidate the mechanisms of lipid metabolism abnormalities in the development of PCOS. (C) 2019 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.

引用

页码：447 / 453

页数：7

共 91 条

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