The role of intragenomic recombination rate in the evolution of population's genetic pool

被引：18

作者：

Zawierta, Marta ^{[1
]}

Biecek, Przemyslaw ^{[1
]}

Waga, Wojciech ^{[1
]}

Cebrat, Stanislaw ^{[1
]}

机构：

[1] Univ Wroclaw, Dept Genom, PL-51148 Wroclaw, Poland

来源：

THEORY IN BIOSCIENCES | 2007年 / 125卷 / 02期

关键词：

Monte Carlo simulation; population evolution; recombination; mutation; recessiveness;

D O I：

10.1016/j.thbio.2007.02.002

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In a simple computer model of population evolution, we have shown that frequency of recombination between haplotypes during the gamete production influences the effectiveness of the reproduction strategy. High recombination rates keeps the fraction of defective alleles low while low recombination rate or uneven distributed recombination spots change the strategy of genomes' evolution and result in the accumulation of heterozygous loci in the genomes. Even short fragment of chromosome with restricted recombination influences the genetic structure of neighboring regions. (C) 2007 Elsevier GmbH. All rights reserved.

引用

页码：123 / 132

页数：10

共 15 条

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