Near Infrared Spectroscopy Combined with Principal Component Analysis Applied to Diagnosis of Endometrial Carcinoma

被引：0

作者：

Xu Ke ^{[1
]}

Xiang Yu-Hong ^{[1
]}

Dai Yin-Mei ^{[2
]}

Zhang Zhuo-Yong ^{[1
]}

机构：

[1] Capital Normal Univ, Dept Chem, Beijing 100048, Peoples R China

[2] Capital Med Univ, Beijing Obstet & Gynecol Hosp, Beijing 100006, Peoples R China

来源：

CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 2009年 / 30卷 / 08期

关键词：

Endometrial carcinoma; Near infrared spectroscopy; Principal component analysis; CANCER;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The feasibility of near infrared (NIR) spectral feature extraction and early diagnosis of endometrial carcinoma were developed by chemometrics methods. Few papers have been reported about the studies on NIR spectra features of endometrial carcinoma so far. In this study, the NIR spectra of 154 specimens of endometrium were collec-ted, and spectral data were analyzed by principal component analysis. In order to improve the classification, selection of wavelength range and spectral pretreatment methods were discussed. The results suggested that samples of malignant, hyperplasia and normal endometrium were classified correctly. Moreover, endometrium at various differentiation stages could also be identified, which provided reliable evidence for early diagnosis in endometrial carcinoma. This approach was proved to be rapid and convenient, which is able to be developed as a non-invasive diagnosis method for cancer.

引用

页码：1543 / 1547

页数：5

共 25 条

[1] Reflectance spectroscopy for diagnosis of epithelial precancer: model-based analysis of fiber-optic probe designs to resolve spectral information from epithelium and stroma [J].

Arifler, D ;

Schwarz, RA ;

Chang, SK ;

Richards-Kortum, R .

APPLIED OPTICS, 2005, 44 (20) :4291-4305

[2] In vivo absorption, scattering, and physiologic properties of 58 malignant breast tumors determined by broadband diffuse optical spectroscopy [J].

Cerussi, Albert ;

Shah, Natasha ;

Hsiang, David ;

Durkin, Amanda ;

Butler, John ;

Tromberg, Bruce J. .

JOURNAL OF BIOMEDICAL OPTICS, 2006, 11 (04)

[3]

Chen J, 2008, SPECTROSC SPECT ANAL, V28, P1806

[4] Infrared spectroscopy of normal and abnormal cervical smears: Evaluation by principal component analysis [J].

Cohenford, MA ;

Godwin, TA ;

Cahn, F ;

Bhandare, P ;

Caputo, TA ;

Rigas, B .

GYNECOLOGIC ONCOLOGY, 1997, 66 (01) :59-65

[5] Vaginal, laparoscopic, or abdominal hysterectomies for benign disorders:: immediate and early postoperative complications [J].

Cosson, M ;

Lambaudie, E ;

Boukerrou, M ;

Querleu, D ;

Crépin, G .

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2001, 98 (02) :231-236

[6] Proteomic analysis of amniotic fluids using analysis of variance-principal component analysis and fuzzy rule-building expert systems applied to matrix-assisted laser desorption/ionization mass spectrometry [J].

Harrington, PD ;

Vieira, NE ;

Chen, P ;

Espinoza, J ;

Nien, JK ;

Romero, R ;

Yergey, AL .

CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 2006, 82 (1-2) :283-293

[7] Analysis of variance-principal component analysis: A soft tool for proteomic discovery [J].

Harrington, PD ;

Vieira, NE ;

Espinoza, J ;

Nien, JK ;

Romero, R ;

Yergey, AL .

ANALYTICA CHIMICA ACTA, 2005, 544 (1-2) :118-127

[8]

[何民富 HE Minfu], 2008, [中国癌症杂志, China Oncology], V18, P517

[9]

HIROYA Y, 2003, RAD MED, V21, P1

[10]

Joliffe I T, 1992, Stat Methods Med Res, V1, P69, DOI 10.1177/096228029200100105

← 1 2 3 →