Outcomes of commercial renal transplantation: A Canadian experience

被引:68
作者
Prasad, G. V. Ramesh
Shukla, Ashutosh
Huang, Michael
D'A Honey, R. John
Zaltzman, Jeffrey S.
机构
[1] Univ Toronto, Dept Med, Div Nephrol, St Michaels Hosp,Renal Transplant Program, Toronto, ON M5B 1W8, Canada
[2] Univ Toronto, Dept Surg, Div Urol, Toronto, ON M5B 1W8, Canada
关键词
commercial renal transplantation; live donor; graft survival; patient survival;
D O I
10.1097/01.tp.0000241072.03400.11
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. Financial compensation in exchange for live kidney donation is prohibited in Canada. However, patients in Canada with end-stage renal disease and without a suitable biologically or emotionally related live donor face substantial waiting times on lists for deceased donor kidneys, and so may therefore choose to acquire organs from a live donor in a procedure performed outside Canada as part of a commercial transaction. Methods. We describe the clinical outcomes in such patients transplanted between 1998 and 2005, managed after their surgery at a single Canadian transplant center. Results. Patient and graft survival at three years were significantly worse in this group compared to recipients of live biologically related (P < 0.0001) and emotionally related transplants (P < 0.01) performed in Canada during this period. A number of different surgical and infectious complications were seen, requiring frequent and often lengthy hospitalization. Conclusion. Patients considering this method of acquiring live-donated kidneys should be counseled of the inherent risks and possible adverse outcomes including diminished dialysis-free survival.
引用
收藏
页码:1130 / 1135
页数:6
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