"A Tale of Two Cities": Anticoagulation Management in Patients with Atrial Fibrillation and Prosthetic Valves in the Era of Direct Oral Anticoagulants

被引：1
|
作者：
Palmiero, Giuseppe [1 ]
Melillo, Enrico [1 ]
Rubino, Antonino Salvatore [2 ]
机构：
[1] AORN Osped Colli Monaldi Hosp, Dept Cardiol, I-80131 Naples, Italy
[2] Univ Campania Luigi Vanvitelli, Dept Translat Med Sci, I-80131 Naples, Italy
来源：
MEDICINA-LITHUANIA | 2019年 / 55卷 / 08期
关键词：
novel oral anticoagulants; prosthetic valve replacement; atrial fibrillation; RHYTHM ASSOCIATION EHRA; VALVULAR HEART-DISEASE; CARDIAC-ARRHYTHMIA SOCIETY; JOINT CONSENSUS DOCUMENT; CARDIOLOGY WORKING GROUP; SOUTHERN AFRICA CASSA; ANTITHROMBOTIC THERAPY; EUROPEAN-SOCIETY; CURRENT CARDIOVERSION; DABIGATRAN;
D O I：
10.3390/medicina55080437
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Valvular heart disease and atrial fibrillation often coexist. Oral vitamin K antagonists have represented the main anticoagulation management for antithrombotic prevention in this setting for decades. Novel direct oral anticoagulants (DOACs) are a new class of drugs and currently, due to their well-established efficacy and security, they represent the main therapeutic option in non-valvular atrial fibrillation. Some new evidences are exploring the role of DOACs in patients with valvular atrial fibrillation (mechanical and biological prosthetic valves). In this review we explore the data available in the medical literature to establish the actual role of DOACs in patients with valvular heart disease and atrial fibrillation.
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页数：9
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