Ulcerative Colitis With Concomitant Serrated Polyposis Syndrome: A Case Report and Literature Review

被引:1
作者
Mansour, Mahmoud M. [1 ]
Smith, Zachary D. [2 ]
Ghouri, Yezaz [2 ]
Tahan, Veysel [2 ]
机构
[1] Univ Missouri, Sch Med, Internal Med, Columbia, MO 65211 USA
[2] Univ Missouri, Sch Med, Internal Med Gastroenterol & Hepatol, Columbia, MO USA
关键词
inflammatory bowel disease; ulcerative colitis (uc); colorectal cancer (crc); sessile serrated adenoma; serrated polyp; serrated polyposis syndrome (sps); INFLAMMATORY-BOWEL-DISEASE; COLORECTAL-CANCER; CASE SERIES; RISK; DYSPLASIA; CONSENSUS; PATHWAY; UPDATE; COHORT;
D O I
10.7759/cureus.14591
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Serrated polyposis syndrome (SPS) is a pre-cancerous condition associated with increased risk of developing colorectal cancer (CRC). Its role in inflammatory bowel disease (IBD)-associated CRC remains unknown. Despite the growing understanding and recognition of SPS, there is limited literature about its impact on the colon in individuals with IBD. Herein, we report a case of a 45-year-old female who was diagnosed with ulcerative colitis (UC) and SPS. We also reviewed the literature surrounding this association and highlighted the intricacies in managing this unique patient population. At present, there are no screening guidelines for CRC in SPS patients with IBD. However, given the potential synergistic risk for CRC, a close surveillance approach may be utilized. Tracking lifetime cumulative features of SPS and endoscopic clearance of adenomas and serrated polyps are the mainstays of management.
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