Spotted leucoderma after treatment of facial hyperpigmentation on hemodialysis patients employing 1064-nm Q-switched Nd:YAG laser

被引:2
作者
Hwang, Chian-Yaw [3 ]
Lin, Chrang-Shi [1 ,2 ]
Tseng, Ming-Li [4 ]
Liu, Han-Nan [3 ]
机构
[1] Natl Yang Ming Univ, Dept Dermatol, Taipei 112, Taiwan
[2] Natl Yang Ming Univ, Dept Family Phys, Taipei 112, Taiwan
[3] Taipei Gen Vet Hosp, Dept Dermatol, Taipei, Taiwan
[4] Dr Tseng Private Skin Clin, Taipei, Taiwan
关键词
Facial hyperpigmentation; hemodialysis; spoued leucoderma; 1064-nm Nd:YAG laser; PIGMENTATION; DIALYSIS; MELASMA; IMPACT;
D O I
10.3109/14764170903352886
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The development of skin hyperpigmentation in patients with end-stage renal disease (ESRD) on hemodialysis (HD) have been well documented. However, the cosmetic concern was neither valued seriously nor treated effectively in the past. We report a female case who suffered from facial hyperpigmentation (FH). She was treated by large-spot sized, 1064-nm Q-switched Nd:YAG laser (QSNYL). A significant improvement was found after three treatment sessions at a fluence of 3.9 J/cm(2) with 8-day intervals, but spotted leucoderma developed at the fourth visit. Neither residual FH nor spotted leucoderma subsequently improved following two additional sessions of 1064-nm QSNYL at a lower fluence with topical hydroquinone and HeNe laser, and it persisted at the 1-year follow-up. This clinically specific round-shaped leucoderma suggested laser-induced damage to melanocytes due to unsuitable application. The 1064-nm QSNYL with a large spot size and an appropriate parameter may become an effective therapeutic modality if properly utilized.
引用
收藏
页码:47 / 50
页数:4
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