Fabrication of Novel Biocompatible Surfaces by Two-Photon Absorption Technique Using Femtosecond Laser

被引：3

作者：

Tanaka, Masaru ^{[1
]}

Sato, Hirokazu ^{[2
]}

Sasaya, Yugo ^{[2
]}

Horinouchi, Suguru ^{[2
]}

Hotta, Jun-ichi ^{[3
]}

Matsuo, Yasutaka ^{[3
]}

Ijiro, Kuniharu ^{[3
]}

Sasaki, Keiji ^{[3
]}

Shimomura, Masatsugu ^{[1
,4
]}

机构：

[1] Tohoku Univ, Inst Multidisciplinary Res Adv Mat, Aoba Ku, Sendai, Miyagi 9808577, Japan

[2] Chitose Inst Sci & Technol, Bibi, Chitose, Japan

[3] Hokkaido Univ, Res Inst Elect Sci, Kita Ku, Sapporo, Hokkaido, Japan

[4] Tohoku Univ, World Premier Int Res Ctr, Adv Inst Mat Res WPI AIMR, Sendai, Miyagi 9808577, Japan

来源：

MOLECULAR CRYSTALS AND LIQUID CRYSTALS | 2009年 / 505卷

关键词：

biocompatible polymer; fabrication; platelet adhesion; poly(2-methoxyethyl acrylate); scaffold; two-photon; POLY(2-METHOXYETHYL ACRYLATE); PROTEIN ADSORPTION; BLOOD COMPATIBILITY; WATER-STRUCTURE; PMEA SURFACE; IN-SITU; MICROFABRICATION; ARCHITECTURES; ADHESION;

D O I：

10.1080/15421400902950121

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This study describes the preparation of biocompatible patterned surfaces by a two-photon absorption technique. We have synthesized poly(2-methoxyethyl acrylate) copolymers, which exhibit biocompatibility and photocrosslinking moiety. Fabrication resolution can be controlled in the sub-micrometer range by changing the laser power, photoinitiator concentration, and scanning speed. The patterned surfaces showed excellent human platelet compatibility. Biocompatible patterned surfaces can be used in various medical devices, implants, biosensor chips, and tissue engineering scaffolds.

引用

页码：457 / 468

页数：12

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