Pathophysiology of colonic causes of chronic constipation

被引:42
作者
Dinning, P. G. [1 ]
Smith, T. K. [2 ]
Scott, S. M. [3 ]
机构
[1] Univ New S Wales, St George Hosp, Dept Med, Sydney, NSW, Australia
[2] Univ Nevada, Sch Med, Dept Physiol & Cell Biol, Reno, NV 89557 USA
[3] Queen Mary Univ London, Barts & London Sch Med & Dent, London, England
基金
澳大利亚国家健康与医学研究理事会;
关键词
colon; constipation; manometry; scintigraphy; marker studies; SLOW-TRANSIT CONSTIPATION; CHRONIC IDIOPATHIC CONSTIPATION; IRRITABLE-BOWEL-SYNDROME; ENTERIC NERVOUS-SYSTEM; MOTOR-ACTIVITY; OBSTRUCTED DEFECATION; GUT TRANSIT; ENDOLUMINAL INSTILLATION; SCINTIGRAPHIC ASSESSMENT; PROPULSIVE IMPAIRMENT;
D O I
10.1111/j.1365-2982.2009.01401.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
P>Colonic sensorimotor dysfunction is recognized as the principal pathophysiological mechanism underpinning chronic constipation. This review addresses current understanding derived from both human and animal studies, with particular reference made to methods of investigation.
引用
收藏
页码:20 / 30
页数:11
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