The Impact of Preexisting or Acquired Kaposi Sarcoma Herpesvirus Infection in Kidney Transplant Recipients on Morbidity and Survival

被引:54
作者
Frances, C. [1 ]
Marcelin, A. G. [2 ]
Legendre, Ch. [3 ]
Chevret, S. [4 ]
Dussaix, E. [5 ]
Lejeune, J. [4 ]
Euvrard, S. [6 ]
Bigorie, A. [8 ]
Schulz, T. F. [7 ]
Agbalika, F. [9 ]
Lebbe, C. [10 ]
机构
[1] Univ Paris 06, Hop Tenon, AP HP, Dept Dermatol Allergol, Paris, France
[2] Univ Paris 06, Hop La Pitie Salpetriere, AP HP, Dept Virol, Paris, France
[3] Univ Paris 05, Hop Necker, AP HP, Dept Nephrol, Paris, France
[4] Univ Paris Diderot, Hop St Louis, AP HP, Dept Biostat, Paris, France
[5] Univ Paris 11, Hop Paul Brousse, AP HP, Dept Microbiol, Villejuif, France
[6] Univ Grange Blanche, Hop Edouard Herriot, Hosp Civils Lyon, Dept Dermatol, Lyon, France
[7] Hannover Med Sch, Inst Virol, D-3000 Hannover, Germany
[8] Agence BioMed, St Denis, France
[9] Univ Paris Diderot, Hop St Louis, AP HP, Dept Microbiol,U716, Paris, France
[10] Univ Paris Diderot, Hop St Louis, AP HP, Dept Dermatol,U716, Paris, France
关键词
Human herpesvirus type 8; Kaposi's sarcoma; Kaposi sarcoma herpesvirus; kidney transplantation; PREVIOUS HUMAN-HERPESVIRUS-8 INFECTION; ORGAN-TRANSPLANTATION; COMPETING RISK; TRANSMISSION; SEROPREVALENCE; TRANSFUSION; PREVALENCE; ANTIBODY; PROTEIN; FRANCE;
D O I
10.1111/j.1600-6143.2009.02816.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
In group A, 13% developed Kaposi's sarcoma (KS). Age > 53.5 years (p = 0.025) and black skin (p = 0.0054) were associated with KS development. In group B, three recipients developed clinical manifestations related to KSHV infection. There was no difference in terms of survival and graft loss between the three groups. In conclusion, although kidney recipients should be aware of the additional risk of KSHV morbidity, KSHV+ recipients should not be systematically excluded from kidney transplantation.
引用
收藏
页码:2580 / 2586
页数:7
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