Cohort Studies: Prospective versus Retrospective

被引：254
作者：
Euser, Anne M.
Zoccali, Carmine [3 ]
Jager, Kitty J. [2 ]
Dekker, Friedo W. [1 ,2 ]
机构：
[1] Leiden Univ, Med Ctr, Dept Clin Epidemiol, Directorate Educ, NL-2100 RC Leiden, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, Dept Med Informat, ERA EDTA Registry, NL-1105 AZ Amsterdam, Netherlands
[3] Osped Riuniti Reggio Calabria, CNR IBIM Clin Epidemiol & Pathophysiol Renal Dis, Renal & Transplantat Unit, Reggio Di Calabria, Italy
来源：
NEPHRON CLINICAL PRACTICE | 2009年 / 113卷 / 03期
关键词：
Epidemiology; Observational studies; Cohort study; Prospective studies; Longitudinal studies; Retrospective studies; Study design; Nephrology;
D O I：
10.1159/000235241
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Cohort studies form a suitable study design to assess associations between multiple exposures on the one hand and multiple outcomes on the other hand. They are especially appropriate to study rare exposures or exposures for which randomization is not possible for practical or ethical reasons. Prospective and retrospective cohort studies have higher accuracy and higher efficiency as their respective main advantages. In addition to possible confounding by indication, cohort studies may suffer from selection bias. Confounding and bias should be prevented whenever possible, but still can exert unknown effects in unknown directions. If one is aware of this, cohort studies can form a potent study design in nephrology producing, in general, highly generalizable results. Copyright (C) 2009 S. Karger AG, Basel
引用
收藏
页码：C214 / C217
页数：4
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