Gold(III) Chloride Catalyzed Synthesis of 1-Cyanoisoindoles

被引：43

作者：

Heugebaert, Thomas S. A. ^{[1
]}

Stevens, Christian V. ^{[1
]}

机构：

[1] Univ Ghent, Res Grp SynBioC, Dept Organ Chem, Fac Biosci Engn, B-9000 Ghent, Belgium

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 21期

关键词：

D O I：

10.1021/ol902031f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A two-step synthesis of 1-cyanoisoindoles starting from ethynylbenzaldehyde is presented. The key step is a mild, high-yielding, gold-catalyzed rearrangement of N-allylic aminonitriles.

引用

页码：5018 / 5021

页数：4

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