Insights into DNA deaminases

被引：29

作者：

Conticello, Silvestro G. ^{[1
]}

Langlois, Marc-Andre ^{[1
]}

Neuberger, Michael S. ^{[1
]}

机构：

[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England

来源：

NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2007年 / 14卷 / 01期

关键词：

D O I：

10.1038/nsmb0107-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structures of APOBEC2 and TadA, members of a superfamily of Zn-dependent deaminases, reveal unexpected features and provide insight into the ability of some family members to act on DNA.

引用

页码：7 / 9

页数：4

共 11 条

[1] RETRACTED: Cellular APOBEC3G restricts HIV-1 infection in resting CD4+ T cells (Retracted Article. See vol 466, pg 276, 2010) [J].

Chiu, YL ;

Soros, VB ;

Kreisberg, JF ;

Stopak, K ;

Yonemoto, W ;

Greene, WC .

NATURE, 2005, 435 (7038) :108-114

[2] An adenosine deaminase that generates inosine at the wobble position of tRNAs [J].

Gerber, AP ;

Keller, W .

SCIENCE, 1999, 286 (5442) :1146-1149

[3] Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains [J].

Hakata, Yoshiyuki ;

Landau, Nathaniel R. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (48) :36624-36631

[4] Retroviral restriction by APOBEC proteins [J].

Harris, RS ;

Liddament, MT .

NATURE REVIEWS IMMUNOLOGY, 2004, 4 (11) :868-877

[5] Mutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA target site specificities [J].

Langlois, MA ;

Beale, RCL ;

Conticello, SG ;

Neuberger, MS .

NUCLEIC ACIDS RESEARCH, 2005, 33 (06) :1913-1923

[6] Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA [J].

Losey, HC ;

Ruthenburg, AJ ;

Verdine, GL .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2006, 13 (02) :153-159

[7] An overview of cytidine deaminases [J].

Navaratnam, N ;

Sarwar, R .

INTERNATIONAL JOURNAL OF HEMATOLOGY, 2006, 83 (03) :195-200

[8] DNA deamination in immunity [J].

Petersen-Mahrt, S .

IMMUNOLOGICAL REVIEWS, 2005, 203 :80-97

[9] The APOBEC-2 crystal structure and functional implications for the deaminase AID [J].

Prochnow, Courtney ;

Bransteitter, Ronda ;

Klein, Michael G. ;

Goodman, Myron F. ;

Chen, Xiaojiang S. .

NATURE, 2007, 445 (7126) :447-451

[10] The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity [J].

Shindo, K ;

Takaori-Kondo, A ;

Kobayashi, M ;

Abudu, A ;

Fukunaga, K ;

Uchiyama, T .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (45) :44412-44416

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