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Establishment of Age- and Gender-Specific Reference Ranges for 36 Routine and 57 Cell Population Data Items in a New Automated Blood Cell Analyzer, Sysmex XN-2000
被引：28
|作者：
Park, Sang Hyuk
[1
,2
,3
,4
]
Park, Chan-Jeoung
[1
,2
]
Lee, Bo-Ra
[1
,2
]
Kim, Mi-Jeong
[1
,2
]
Han, Min-Young
[1
,2
]
Cho, Young-Uk
[1
,2
]
Jang, Seongsoo
[1
,2
]
机构：
[1] Univ Ulsan, Coll Med, Dept Lab Med, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea
[2] Asan Med Ctr, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea
[3] Pusan Natl Univ, Sch Med, Pusan Natl Univ Hosp, Dept Lab Med, Busan, South Korea
[4] Pusan Natl Univ Hosp, Biomed Res Inst, Busan, South Korea
关键词：
Age;
Automated blood cell analyzer;
Gender;
Item;
Reference range;
Sysmex XN-2000;
REFERENCE INTERVALS;
XE-2100;
D O I：
10.3343/alm.2016.36.3.244
中图分类号：
R446 [实验室诊断];
R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
We established age- and gender-specific reference ranges for the 36 routine complete blood cell (CBC) and 57 cell population data (CPD) items in the Sysmex XN-2000 (Sysmex, Japan). In total, 280 peripheral blood samples were obtained from an equal number of healthy adults. Values for 36 routine items and 57 CPD items were obtained for each sample, and the results were categorized into six subgroups (N>39 in each subgroup) according to patient age (20-40, 41-60, and >60 yr) and gender (male and female), and compared with respect to age and gender differences. The majority of data items (22 of 36 routine CBC items and 44 of 57 CPD items) exhibited significant differences.(P <= 0.05) in their results with respect to age or gender, and several red cell-, lymphocyte-, and platelet-related data tended to decrease in women or older adults. These results provide a basis for establishing age- and gender-specific reference ranges for routine and CPD items in Sysmex XN-2000. Furthermore, these reference ranges could be used to determine clinical significance for new items of Sysmex XN-2000 in further studies.
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页码：244 / 249
页数：6
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