Aryne-induced dearomatized phosphonylation of electron-deficient azaarenes

被引：32
作者：
Liu, Kai [1 ]
Liu, Li-Li [1 ]
Gu, Cheng-Zhi [1 ]
Dai, Bin [1 ]
He, Lin [1 ]
机构：
[1] Shihezi Univ, Sch Chem & Chem Engn, Xinjiang Autonomous Regi 832000, Peoples R China
来源：
RSC ADVANCES | 2016年 / 6卷 / 40期
基金：
中国国家自然科学基金;
关键词：
ASYMMETRIC ALLYLIC DEAROMATIZATION; CHIRAL PHOSPHORIC-ACID; ENANTIOSELECTIVE SYNTHESIS; TRANSFER HYDROGENATION; BETA-PHENYLETHYLAMINES; PHENOL DEAROMATIZATION; TANDEM REACTION; INDOLES; TETRAHYDROQUINOLINES; QUINOLINES;
D O I：
10.1039/c6ra02128j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An aryne-induced dearomatized phosphonylation reaction has been developed. Electron-deficient azaarenes such as quinolines, isoquinolines, phenanthroline and acridine undergo multicomponent reaction with arynes and dialkylphosphites to afford the corresponding dearomatized phosphonylated heterocycles in 50-90% yields.
引用
收藏
页码：33606 / 33610
页数：5
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