Is There a Relationship between COVID-19 and Hyponatremia?

被引：45

作者：

Gheorghe, Gina ^{[1
,2
]}

Ilie, Madalina ^{[1
,2
]}

Bungau, Simona ^{[3
]}

Stoian, Anca Mihaela Pantea ^{[4
]}

Bacalbasa, Nicolae ^{[5
]}

Diaconu, Camelia Cristina ^{[6
,7
]}

机构：

[1] Carol Davila Univ Med & Pharm, Dept Gastroenterol, Bucharest 050474, Romania

[2] Clin Emergency Hosp Bucharest, Dept Gastroenterol, Bucharest 105402, Romania

[3] Univ Oradea, Fac Med & Pharm, Dept Pharm, Oradea 410028, Romania

[4] Carol Davila Univ Med & Pharm, Dept Diabet Nutr & Metab Dis, Bucharest 020475, Romania

[5] Fundeni Clin Inst, Dept Visceral Surg, Ctr Excellence Translat Med, Bucharest 022328, Romania

[6] Carol Davila Univ Med & Pharm, Dept Internal Med, Bucharest 050474, Romania

[7] Clin Emergency Hosp Bucharest, Dept Internal Med, Bucharest 105402, Romania

来源：

MEDICINA-LITHUANIA | 2021年 / 57卷 / 01期

关键词：

SARS-CoV-2; COVID-19; SIADH; dyselectrolytemia; hyponatremia; CLINICAL CHARACTERISTICS; OUTCOMES;

D O I：

10.3390/medicina57010055

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nowadays, humanity faces one of the most serious health crises, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The severity of coronavirus disease 2019 (COVID-19) pandemic is related to the high rate of interhuman transmission of the virus, variability of clinical presentation, and the absence of specific therapeutic methods. COVID-19 can manifest with non-specific symptoms and signs, especially among the elderly. In some cases, the clinical manifestations of hyponatremia may be the first to appear. The pathophysiological mechanisms of hyponatremia among patients with COVID-19 are diverse, including syndrome of inappropriate antidiuretic hormone secretion (SIADH), digestive loss of sodium ions, reduced sodium ion intake or use of diuretic therapy. Hyponatremia may also be considered a negative prognostic factor in patients diagnosed with COVID-19. We need further studies to evaluate the etiology and therapeutic management of hyponatremia in patients with COVID-19.

引用

页码：1 / 7

页数：7

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