Noncoding RNAs in exercise-induced cardio-protection for chronic heart failure

被引:11
|
作者
Ma, Siyuan [1 ]
Liao, Yulin [1 ]
机构
[1] Southern Med Univ, Nanfang Hosp, State Key Lab Organ Failure Res, Dept Cardiol, Guangzhou 510515, Guangdong, Peoples R China
来源
EBIOMEDICINE | 2019年 / 46卷
基金
中国国家自然科学基金;
关键词
Noncoding RNAs; Exercise; Chronic heart failure; Therapeutic target; LEFT-VENTRICULAR HYPERTROPHY; CIRCULAR RNA; SYNERGISTIC REGULATION; MYOCARDIAL-INFARCTION; CA2+ OVERLOAD; LNCRNA MALAT1; MICRORNAS; DYSFUNCTION; MECHANISMS; APOPTOSIS;
D O I
10.1016/j.ebiom.2019.07.051
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chronic heart failure (CHF) has long been a major medical care burden on society due to its high morbidity and mortality. Although lots of evidence has demonstrated the beneficial impacts of exercise on CHF, termed exercise-induced cardioprotection (EIC), the underlying mechanisms and applicability of Ware elusive and controversial, and thus, clinical applications are difficult. Noncoding RNAs (ncRNAs) are potential therapeutic targets for CHF. Increasing number of ncRNAs were found to play a role in EIC and CHF. The purpose of this review is to illustrate the current knowledge of ncRNAs in EIC for CHF as well as their prospective and limitations in clinical application. (C) 2019 The Authors. Published by Elsevier B.V.
引用
收藏
页码:532 / 540
页数:9
相关论文
共 50 条
  • [41] Novel Gasotransmitter Cardio-Protection in the Developing Heart: Comparative Roles of Hydrogen Sulphide and Carbon Monoxide.
    Niu, Y.
    Lyu, Q.
    Hess, R. M.
    Ford, S. G.
    Garrud, T. A.
    Iqbal, A.
    Louca, J. O.
    Tong, W.
    Botting, K. J.
    Giussani, D. A.
    REPRODUCTIVE SCIENCES, 2020, 27 (SUPPL 1) : 108A - 108A
  • [42] Exercise-Induced Left Atrial Hypertension in Heart Failure With Preserved Ejection Fraction
    Litwin, Sheldon E.
    Komtebedde, Jan
    Hu, Mo
    Burkhoff, Daniel
    Hasenfuss, Gerd
    Borlaug, Barry A.
    Solomon, Scott D.
    Zile, Michael R.
    Mohan, Rajeev C.
    Khawash, Rami
    Sverdlov, Aaron L.
    Fail, Peter
    Chung, Eugene S.
    Kaye, David M.
    Blair, John
    Eicher, Jean-Christophe
    Hummel, Scott L.
    Zirlik, Andreas
    Westenfeld, Ralf
    Hayward, Christopher
    Gorter, Thomas M.
    Demers, Catherine
    Shetty, Ranjith
    Lewis, Gregory
    Starling, Randall C.
    Patel, Sanjay
    Gupta, Deepak K.
    Morsli, Hakim
    Penicka, Martin
    Cikes, Maja
    Gustafsson, Finn
    Silvestry, Frank E.
    Rowin, Ethan J.
    Cutlip, Donald E.
    Leon, Martin B.
    Kitzman, Dalane W.
    Kleber, Franz X.
    Shah, Sanjiv J.
    JACC-HEART FAILURE, 2023, 11 (08) : 1103 - 1117
  • [43] Basal and exercise-induced neuroendocrine activation in patients with heart failure and in normal subjects
    Kjær, A
    Appel, J
    Hildebrandt, P
    Petersen, CL
    EUROPEAN JOURNAL OF HEART FAILURE, 2004, 6 (01) : 29 - 39
  • [44] Exercise-induced tricuspid regurgitation in heart failure, gas exchange profile and outcomes
    Mondellini, G. M.
    Rusconi, I.
    Giustiniani, A.
    Landi, S.
    Dinardo, G.
    Bursi, F.
    Guazzi, M.
    EUROPEAN JOURNAL OF HEART FAILURE, 2024, 26 : 469 - 469
  • [45] DRUG PROTECTION AGAINST EXERCISE-INDUCED ASTHMA
    SCHERRER, M
    ALLERGOLOGIE, 1983, 6 (04) : 134 - 140
  • [46] Chronic heart failure and exercise
    Kokkinos, PF
    Choucair, W
    Graves, P
    Papademetriou, V
    Ellahham, S
    AMERICAN HEART JOURNAL, 2000, 140 (01) : 21 - 28
  • [47] Exercise in Chronic Heart Failure
    Pressler, Axel
    AKTUELLE KARDIOLOGIE, 2020, 9 (02) : 171 - 178
  • [48] EXERCISE-INDUCED CHANGES IN SERUM POTASSIUM IN PATIENTS WITH CHRONIC-RENAL-FAILURE
    DAUL, AE
    VOLKER, K
    HERING, D
    SCHAFERS, RF
    PHILIP, T
    KIDNEY INTERNATIONAL, 1995, 47 (03) : 969 - 969
  • [49] EXERCISE-INDUCED COMPLETE HEART-BLOCK IN A PATIENT WITH CHRONIC BIFASCICULAR BLOCK
    BYRNE, JM
    MARAIS, HJ
    CHEEK, GA
    JOURNAL OF ELECTROCARDIOLOGY, 1994, 27 (04) : 339 - 342
  • [50] EXERCISE-INDUCED CHANGES IN LEFT-VENTRICULAR FUNCTION VALUES OF PATIENTS WITH CHRONIC HEART-FAILURE - A RADIONUCLIDE STUDY
    FAIVRE, R
    BASSAND, JP
    DUCELLIER, D
    SCHIELE, F
    VERDENET, J
    CARDOT, JC
    BAUD, M
    MAURAT, JP
    ARCHIVES DES MALADIES DU COEUR ET DES VAISSEAUX, 1988, 81 (07): : 865 - 869