Spleen modulation of cytoadherence properties of Plasmodium falciparum

被引：6

作者：

Munasinghe, Anjanie ^{[2
]}

Ileperuma, Manjula ^{[2
]}

Premawansa, Gayani ^{[3
]}

Handunnetti, Shiroma ^{[4
]}

Premawansa, Sunil ^{[1
,2
]}

机构：

[1] Univ Colombo, Fac Sci, Dept Zool, Colombo 3, Sri Lanka

[2] Univ Colombo, Fac Sci, Dept Parasitol, Malaria Res Unit, Colombo 3, Sri Lanka

[3] Dist Gen Hosp, Gampaha, Sri Lanka

[4] Univ Colombo, Inst Biochem Mol Biol & Biotechnol, Colombo 3, Sri Lanka

来源：

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES | 2009年 / 41卷 / 6-7期

关键词：

MALARIA; ERYTHROCYTES;

D O I：

10.1080/00365540902971195

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Cytoadherence to CD36 and ICAM-1 and var gene expression of P. falciparum parasites from a splenectomized patient were studied. These parasites lacked cytoadherence and showed expression of a non-coding cDNA sequence. Hence the spleen's modulation of parasite cytoadherence by mechanisms that affect the parasite's surface antigen expression is suggested.

引用

页码：538 / 539

页数：2

共 6 条

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