Using X-ray free-electron lasers for spectroscopy of molecular catalysts and metalloenzymes

被引：78

作者：

Bergmann, Uwe ^{[1
,2
]}

Kern, Jan ^{[3
]}

Schoenlein, Robert W. ^{[1
,4
]}

Wernet, Philippe ^{[5
]}

Yachandra, Vittal K. ^{[3
]}

Yano, Junko ^{[3
]}

机构：

[1] SLAC Natl Accelerator Lab, Stanford PULSE Inst, Menlo Pk, CA 94025 USA

[2] Univ Wisconsin, Dept Phys, 1150 Univ Ave, Madison, WI 53706 USA

[3] Lawrence Berkeley Natl Lab, Mol Biophys & Integrated Bioimaging Div, Berkeley, CA 94720 USA

[4] SLAC Natl Accelerator Lab, Linac Coherent Light Source, Menlo Pk, CA 94025 USA

[5] Uppsala Univ, Dept Phys & Astron, Uppsala, Sweden

来源：

NATURE REVIEWS PHYSICS | 2021年 / 3卷 / 04期

基金：

美国国家卫生研究院;

关键词：

186;

D O I：

10.1038/s42254-021-00289-3

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

X-ray lasers offer unprecedented capabilities, with their tunable, intense and short X-ray pulses. This Technical Review discusses the current and future use of X-ray lasers for probing molecular catalysts and metalloenzymes and their chemical reactions in real time and under functional conditions. The metal centres in metalloenzymes and molecular catalysts are responsible for the rearrangement of atoms and electrons during complex chemical reactions, and they enable selective pathways of charge and spin transfer, bond breaking/making and the formation of new molecules. Mapping the electronic structural changes at the metal sites during the reactions gives a unique mechanistic insight that has been difficult to obtain to date. The development of X-ray free-electron lasers (XFELs) enables powerful new probes of electronic structure dynamics to advance our understanding of metalloenzymes. The ultrashort, intense and tunable XFEL pulses enable X-ray spectroscopic studies of metalloenzymes, molecular catalysts and chemical reactions, under functional conditions and in real time. In this Technical Review, we describe the current state of the art of X-ray spectroscopy studies at XFELs and highlight some new techniques currently under development. With more XFEL facilities starting operation and more in the planning or construction phase, new capabilities are expected, including high repetition rate, better XFEL pulse control and advanced instrumentation. For the first time, it will be possible to make real-time molecular movies of metalloenzymes and catalysts in solution, while chemical reactions are taking place.

引用

页码：264 / 282

页数：19

共 186 条

[1] Generation of Coherent 19-and 38-nm Radiation at a Free-Electron Laser Directly Seeded at 38 nm [J].

Ackermann, S. ;

Azima, A. ;

Bajt, S. ;

Boedewadt, J. ;

Curbis, F. ;

Dachraoui, H. ;

Delsim-Hashemi, H. ;

Drescher, M. ;

Duesterer, S. ;

Faatz, B. ;

Felber, M. ;

Feldhaus, J. ;

Hass, E. ;

Hipp, U. ;

Honkavaara, K. ;

Ischebeck, R. ;

Khan, S. ;

Laarmann, T. ;

Lechner, C. ;

Maltezopoulos, Th. ;

Miltchev, V. ;

Mittenzwey, M. ;

Rehders, M. ;

Roensch-Schulenburg, J. ;

Rossbach, J. ;

Schlarb, H. ;

Schreiber, S. ;

Schroedter, L. ;

Schulz, M. ;

Schulz, S. ;

Tarkeshian, R. ;

Tischer, M. ;

Wacker, V. ;

Wieland, M. .

PHYSICAL REVIEW LETTERS, 2013, 111 (11)

[2]

Agarwal B.K., 1991, XRAY SPECTROSCOPY IN

[3] RELAXATION AND CORRELATION CONTRIBUTIONS TO MOLECULAR DOUBLE CORE IONIZATION ENERGIES [J].

AGREN, H ;

JENSEN, HJA .

CHEMICAL PHYSICS, 1993, 172 (01) :45-57

[4] The FERMI free-electron lasers [J].

Allaria, E. ;

Badano, L. ;

Bassanese, S. ;

Capotondi, F. ;

Castronovo, D. ;

Cinquegrana, P. ;

Danailov, M. B. ;

D'Auria, G. ;

Demidovich, A. ;

De Monte, R. ;

De Ninno, G. ;

Di Mitri, S. ;

Diviacco, B. ;

Fawley, W. M. ;

Ferianis, M. ;

Ferrari, E. ;

Gaio, G. ;

Gauthier, D. ;

Giannessi, L. ;

Iazzourene, F. ;

Kurdi, G. ;

Mahne, N. ;

Nikolov, I. ;

Parmigiani, F. ;

Penco, G. ;

Raimondi, L. ;

Rebernik, P. ;

Rossi, F. ;

Roussel, E. ;

Scafuri, C. ;

Serpico, C. ;

Sigalotti, P. ;

Spezzani, C. ;

Svandrlik, M. ;

Svetina, C. ;

Trovo, M. ;

Veronese, M. ;

Zangrando, D. ;

Zangrando, M. .

JOURNAL OF SYNCHROTRON RADIATION, 2015, 22 :485-491

[5] Two-colour pump-probe experiments with a twin-pulse-seed extreme ultraviolet free-electron laser [J].

Allaria, E. ;

Bencivenga, F. ;

Borghes, R. ;

Capotondi, F. ;

Castronovo, D. ;

Charalambous, P. ;

Cinquegrana, P. ;

Danailov, M. B. ;

De Ninno, G. ;

Demidovich, A. ;

Di Mitri, S. ;

Diviacco, B. ;

Fausti, D. ;

Fawley, W. M. ;

Ferrari, E. ;

Froehlich, L. ;

Gauthier, D. ;

Gessini, A. ;

Giannessi, L. ;

Ivanov, R. ;

Kiskinova, M. ;

Kurdi, G. ;

Mahieu, B. ;

Mahne, N. ;

Nikolov, I. ;

Masciovecchio, C. ;

Pedersoli, E. ;

Penco, G. ;

Raimondi, L. ;

Serpico, C. ;

Sigalotti, P. ;

Spampinati, S. ;

Spezzani, C. ;

Svetina, C. ;

Trovo, M. ;

Zangrando, M. .

NATURE COMMUNICATIONS, 2013, 4

[6]

Allaria E, 2012, NAT PHOTONICS, V6, P699, DOI [10.1038/NPHOTON.2012.233, 10.1038/nphoton.2012.233]

[7] Towards characterization of photo-excited electron transfer and catalysis in natural and artificial systems using XFELs [J].

Alonso-Mori, R. ;

Asa, K. ;

Bergmann, U. ;

Brewster, A. S. ;

Chatterjee, R. ;

Cooper, J. K. ;

Frei, H. M. ;

Fuller, F. D. ;

Goggins, E. ;

Gul, S. ;

Fukuzawa, H. ;

Iablonskyi, D. ;

Ibrahim, M. ;

Katayama, T. ;

Kroll, T. ;

Kumagai, Y. ;

McClure, B. A. ;

Messinger, J. ;

Motomura, K. ;

Nagaya, K. ;

Nishiyama, T. ;

Saracini, C. ;

Sato, Y. ;

Sauter, N. K. ;

Sokaras, D. ;

Takanashi, T. ;

Togashi, T. ;

Ueda, K. ;

Weare, W. W. ;

Weng, T-C ;

Yabashi, M. ;

Yachandra, V. K. ;

Young, I. D. ;

Zouni, A. ;

Kern, J. F. ;

Yano, J. .

FARADAY DISCUSSIONS, 2016, 194 :621-638

[8] Femtosecond electronic structure response to high intensity XFEL pulses probed by iron X-ray emission spectroscopy [J].

Alonso-Mori, Roberto ;

Sokaras, Dimosthenis ;

Cammarata, Marco ;

Ding, Yuantao ;

Feng, Yiping ;

Fritz, David ;

Gaffney, Kelly J. ;

Hastings, Jerome ;

Kao, Chi-Chang ;

Lemke, Henrik T. ;

Maxwell, Timothy ;

Robert, Aymeric ;

Schropp, Andreas ;

Seiboth, Frank ;

Sikorski, Marcin ;

Song, Sanghoon ;

Weng, Tsu-Chien ;

Zhang, Wenkai ;

Glenzer, Siegfried ;

Bergmann, Uwe ;

Zhu, Diling .

SCIENTIFIC REPORTS, 2020, 10 (01)

[9] Energy-dispersive X-ray emission spectroscopy using an X-ray free-electron laser in a shot-by-shot mode [J].

Alonso-Mori, Roberto ;

Kern, Jan ;

Gildea, Richard J. ;

Sokaras, Dimosthenis ;

Weng, Tsu-Chien ;

Lassalle-Kaiser, Benedikt ;

Rosalie Tran ;

Hattne, Johan ;

Laksmono, Hartawan ;

Hellmich, Julia ;

Gloeckner, Carina ;

Echols, Nathaniel ;

Sierra, Raymond G. ;

Schafer, Donald W. ;

Sellberg, Jonas ;

Kenney, Christopher ;

Herbst, Ryan ;

Pines, Jack ;

Hart, Philip ;

Herrmann, Sven ;

Grosse-Kunstleve, Ralf W. ;

Latimer, Matthew J. ;

Fry, Alan R. ;

Messerschmidt, Marc M. ;

Miahnahri, Alan ;

Seibert, M. Marvin ;

Zwart, Petrus H. ;

White, William E. ;

Adams, Paul D. ;

Bogan, Michael J. ;

Boutet, Sebastien ;

Williams, Garth J. ;

Zouni, Athina ;

Messinger, Johannes ;

Glatzel, Pieter ;

Sauter, Nicholas K. ;

Yachandra, Vittal K. ;

Yano, Junko ;

Bergmann, Uwe .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (47) :19103-19107

[10]

Amann J, 2012, NAT PHOTONICS, V6, P693, DOI [10.1038/NPHOTON.2012.180, 10.1038/nphoton.2012.180]

← 1 2 3 4 5 6 7 8 9 10 →