Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring

被引：26

作者：

Pinto, Marco ^{[1
,3
]}

Dauvergne, Denis ^{[1
]}

Freud, Nicolas ^{[2
]}

Krimmer, Jochen ^{[1
]}

Letang, Jean M. ^{[2
]}

Testa, Etienne ^{[1
]}

机构：

[1] Univ Lyon 1, CNRS, UMR 5822, IN2P3,IPNL, F-69622 Villeurbanne, France

[2] Univ Lyon 1, Ctr Leon Berard, INSA Lyon, CREATIS,CNRS,UMR 5220,INSERM,U1044, F-69365 Lyon, France

[3] Univ Munich, Munich, Germany

来源：

FRONTIERS IN ONCOLOGY | 2016年 / 6卷

关键词：

proton therapy; hadrontherapy; prompt gammas; Geant4; online monitoring; in-beam monitoring; collimated camera; nuclear fragmentation models; ION-BEAM THERAPY; RANGE VERIFICATION; SLIT CAMERA; SIMULATION;

D O I：

10.3389/fonc.2016.00010

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Monte Carlo tools have been long used to assist the research and development of solutions for proton therapy monitoring. The present work focuses on the prompt-gamma emission yields by comparing experimental data with the outcomes of the current version of Geant4 using all applicable proton inelastic models. For the case in study and using the binary cascade model, it was found that Geant4 overestimates the prompt-gamma emission yields by 40.2 +/- 0.3%, even though it predicts the prompt-gamma profile length of the experimental profile accurately. In addition, the default implementations of all proton inelastic models show an overestimation in the number of prompt gammas emitted. Finally, a set of built-in options and physically sound Geant4 source code changes have been tested in order to try to improve the discrepancy observed. A satisfactory agreement was found when using the QMD model with a wave packet width equal to 1.3 fm(2).

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