Triflic anhydride-mediated tandem formylation/cyclization of cyanoacetanilides: a concise synthesis of glycocitlone alkaloids

被引：18

作者：

Kobayashi, Yusuke ^{[1
]}

Harayama, Takashi ^{[1
]}

机构：

[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Kanagawa 7692193, Japan

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 48期

基金：

日本学术振兴会;

关键词：

ONE-POT SYNTHESIS; DIVERSITY-ORIENTED SYNTHESIS; MULTICOMPONENT REACTIONS; VILSMEIER REAGENTS; FUSED PYRIDINES; QUINOLINES; CYCLIZATION; DERIVATIVES; INHIBITORS; EFFICIENT;

D O I：

10.1016/j.tetlet.2009.09.073

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method is presented for the concise synthesis of 3-formyl-4-hydroxyquinolin-2(1H)-ones through triflic anhydride-mediated tandem formylation/cyclization of cyanoacetanilides. This tandem process was successfully used for the rapid syntheses of glycocitlones A and C. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：6665 / 6667

页数：3

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