The Association between Age-Related Macular Degeneration and the Risk of Mortality

被引：4
作者：
Wang, Peipei [1 ,2 ,3 ]
Wang, Jie [1 ,2 ]
Ma, Jun [1 ,2 ]
Jin, Ge [1 ,2 ]
Guan, Xueqiang [1 ,2 ]
机构：
[1] Wenzhou Med Univ, Affiliated Hosp 2, Dept Cardiol, Xueyuanxi Rd 109, Wenzhou 325000, Zhejiang, Peoples R China
[2] Wenzhou Med Univ, Yuying Childrens Hosp, Xueyuanxi Rd 109, Wenzhou 325000, Zhejiang, Peoples R China
[3] Wenzhou City Hosp Tradit Chinese Med & Western Me, Dept Neurol, Wenzhou, Peoples R China
来源：
BIOMED RESEARCH INTERNATIONAL | 2017年 / 2017卷
关键词：
VISUAL IMPAIRMENT; EYE DISEASES; METAANALYSIS; SURVIVAL; VISION; WOMEN;
D O I：
10.1155/2017/3489603
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searched PubMed and EMBASE for trials published from 1980 to 2016. We included 11 cohort studies that reported relative risks with 95% confidence intervals for the association of AMD and mortality, involving 57,069 participants. In a random-effects model, the adjusted RR (95% confidence interval) associated with AMD was 1.09 (1.02-1.17) for all-cause mortality. Findings from this research provide support that persons with AMD had a higher subsequent risk of mortality than persons without AMD.
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页数：7
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