Socioeconomic Predictors of Cognition in Ugandan Children: Implications for Community Interventions

被引:71
作者
Bangirana, Paul
John, Chandy C.
Idro, Richard
Opoka, Robert O.
Byarugaba, Justus
Jurek, Anne M.
Boivin, Michael J.
机构
[1] Department of Psychiatry, Makerere University School of Medicine, Kampala
[2] Department of Public Health Sciences, Karolinska Institutet, Stockholm
[3] Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN
[4] Department of Paediatrics and Child Health, Mulago Hospital, Makerere University School of Medicine, Kampala
[5] International Neurologic and Psychiatric Epidemiology Program (INPEP), Michigan State University, East Lansing, MI
[6] Neuropsychology Section, Department of Psychiatry, University of Michigan, Ann Arbor, MI
来源
PLOS ONE | 2009年 / 4卷 / 11期
关键词
CEREBRAL MALARIA; DEVELOPING-COUNTRIES; HOME-ENVIRONMENT; KENYAN CHILDREN; WORKING-MEMORY; ABILITY; AGE; HIPPOCAMPAL; IMPAIRMENT; STRATEGIES;
D O I
10.1371/journal.pone.0007898
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background: Several interventions to improve cognition in at risk children have been suggested. Identification of key variables predicting cognition is necessary to guide these interventions. This study was conducted to identify these variables in Ugandan children and guide such interventions. Methods: A cohort of 89 healthy children (45 females) aged 5 to 12 years old were followed over 24 months and had cognitive tests measuring visual spatial processing, memory, attention and spatial learning administered at baseline, 6 months and 24 months. Nutritional status, child's educational level, maternal education, socioeconomic status and quality of the home environment were also measured at baseline. A multivariate, longitudinal model was then used to identify predictors of cognition over the 24 months. Results: A higher child's education level was associated with better memory (p = 0.03), attention (p = 0.005) and spatial learning scores over the 24 months (p = 0.05); higher nutrition scores predicted better visual spatial processing (p = 0.002) and spatial learning scores (p = 0.008); and a higher home environment score predicted a better memory score (p = 0.03). Conclusion: Cognition in Ugandan children is predicted by child's education, nutritional status and the home environment. Community interventions to improve cognition may be effective if they target multiple socioeconomic variables.
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页数:6
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