A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation

被引:143
作者
Duan, DS
Yue, YP
Yan, ZY
Engelhardt, JF
机构
[1] Univ Iowa, Coll Med, Dept Anat & Cell Biol, Iowa City, IA 52242 USA
[2] Univ Iowa, Coll Med, Ctr Gene Therapy, Iowa City, IA 52242 USA
[3] Univ Iowa, Coll Med, Dept Internal Med, Iowa City, IA 52242 USA
关键词
D O I
10.1038/75080
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:595 / 598
页数:4
相关论文
共 9 条
[1]   Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue [J].
Duan, DS ;
Sharma, P ;
Yang, JS ;
Yue, YP ;
Dudus, L ;
Zhang, YL ;
Fisher, KJ ;
Engelhardt, JF .
JOURNAL OF VIROLOGY, 1998, 72 (11) :8568-8577
[2]   Structural analysis of adeno-associated virus transduction circular intermediates [J].
Duan, DS ;
Yan, ZY ;
Yue, YP ;
Engelhardt, JF .
VIROLOGY, 1999, 261 (01) :8-14
[3]   Structural and functional heterogeneity of integrated recombinant AAV genomes [J].
Duan, DS ;
Fisher, KJ ;
Burda, JF ;
Engelhardt, JF .
VIRUS RESEARCH, 1997, 48 (01) :41-56
[4]   Formation of adeno-associated virus circular genomes is differentially regulated by adenovirus E4 ORF6 and E2a gene expression [J].
Duan, DS ;
Sharma, P ;
Dudus, L ;
Zhang, YL ;
Sanlioglu, S ;
Yan, ZY ;
Yue, YP ;
Ye, YH ;
Lester, R ;
Yang, J ;
Fisher, KJ ;
Engelhardt, JF .
JOURNAL OF VIROLOGY, 1999, 73 (01) :161-169
[5]  
FLOTTE TR, 1993, J BIOL CHEM, V268, P3781
[6]  
LEWIN B, 1997, GENES, V6, P1260
[7]   A RECOMBINANT PLASMID FROM WHICH AN INFECTIOUS ADENOASSOCIATED VIRUS GENOME CAN BE EXCISED INVITRO AND ITS USE TO STUDY VIRAL REPLICATION [J].
SAMULSKI, RJ ;
CHANG, LS ;
SHENK, T .
JOURNAL OF VIROLOGY, 1987, 61 (10) :3096-3101
[8]   Efficient and persistent gene transfer of AAV-CFTR in maxillary sinus [J].
Wagner, JA ;
Reynolds, T ;
Moran, ML ;
Moss, RB ;
Wine, JJ ;
Flotte, TR ;
Gardner, P .
LANCET, 1998, 351 (9117) :1702-1703
[9]   Concatamerization of adeno-associated virus circular genomes occurs through intermolecular recombination [J].
Yang, JS ;
Zhou, WH ;
Zhang, YL ;
Zidon, T ;
Ritchie, T ;
Engelhardt, JF .
JOURNAL OF VIROLOGY, 1999, 73 (11) :9468-9477