Evaluation of the Antidiabetic Potential of Five Medicinal Plants in Rats

被引：0

作者：

Souza, Vagner H. ^{[1
]}

Barbosa, Ana P. O. ^{[1
]}

Cardoso, Geovanna C. ^{[1
]}

Marreto, Ricardo N. ^{[1
]}

Barreto-Filho, Jose A. S. ^{[2
]}

Antoniolli, Angelo R. ^{[1
]}

Santos, Marcio R. V. ^{[1
]}

机构：

[1] Univ Fed Sergipe, Dept Fisiol, BR-49100000 Sao Cristovao, SE, Brazil

[2] Univ Fed Sergipe, Dept Med, BR-49100000 Sao Cristovao, SE, Brazil

来源：

LATIN AMERICAN JOURNAL OF PHARMACY | 2009年 / 28卷 / 04期

关键词：

Anti-hyperglycemic; Aqueous extracts; Diabetes mellitus; Rat; DIABETIC RATS; EXTRACT;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

"Evaluation of the Antidiabetic Potential of Five Medicinal Plants in Rats". Potential antidiabetic activity of five medicinal plants indicated to diabetes was evaluated in normoglicemic rats. Metformin (500 mg/kg) and aqueous extract of Bowdichia virgilioides Kunth (EABV), Costus spicatus Swartz (EACS), Chrysobalanus icaco L. (EACI), Bumelia sartorum Mart (EABS) and Caesalpinia ferrea Mart (EACF), in a single dose of 200 mg/kg, were tested on the curve of glucose tolerance oral test. In this test, only metformina, EABV and EACF were able to inhibit the glucose-induced hyperglycemia up to 46.5, 51.7 e 48.3%, respectively. In conclusion, of the five plants tested, two plants showed anti-hyperglycemic effect that can indicate possible antidiabetic action, in according with popular use.

引用

页码：609 / 612

页数：4

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