Co-infection of Staphylococcus aureus or Haemophilus paragallinarum exacerbates H9N2 influenza A virus infection in chickens

被引:167
作者
Kishida, N
Sakoda, Y
Eto, M
Sunaga, Y
Kida, H [1 ]
机构
[1] Hokkaido Univ, Grad Sch Vet Med, Dept Dis Control, Microbiol Lab, Sapporo, Hokkaido 0600818, Japan
[2] Minist Agr Forestry & Fisheries, Anim Quarantine Serv, Yokohama, Kanagawa, Japan
关键词
D O I
10.1007/s00705-004-0372-1
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
H9N2 influenza viruses are frequently isolated from chicken meat and bone marrow imported from China to Japan since 2001. These isolates were experimentally inoculated into specific pathogen-free chickens intranasally. Viruses were recovered from the meat and bone marrow of birds showing no overt signs. On the other hand, chickens co-infected with H9N2 virus and either Staphylococcus aureus or Haemophilus paragallinarum showed clinical signs severer than those shown by birds infected only with the virus alone or each of the bacteria alone. In addition, H9N2 viruses were more efficiently recovered from the chickens co-infected with S. aureus or H. paragallinarum than those from the birds infected with only the virus. The present results indicate that co-infection of H9N2 influenza virus with S. aureus or H. paragallinarum enhances the replication of the virus in chickens, resulting in exacerbation of the H9N2 virus infection.
引用
收藏
页码:2095 / 2104
页数:10
相关论文
共 23 条
  • [1] A review of avian influenza in different bird species
    Alexander, DJ
    [J]. VETERINARY MICROBIOLOGY, 2000, 74 (1-2) : 3 - 13
  • [2] Heterogeneity of Staphylococci and other bacteria isolated from six-week-old broiler chickens
    Awan, MA
    Matsumoto, M
    [J]. POULTRY SCIENCE, 1998, 77 (07) : 944 - 949
  • [3] Infectious coryza: Overview of the disease and new diagnostic options
    Blackall, PJ
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 1999, 12 (04) : 627 - +
  • [4] STRUCTURE OF THE HEMAGGLUTININ, A DETERMINANT FOR THE PATHOGENICITY OF INFLUENZA-VIRUSES
    BOSCH, FX
    ORLICH, M
    KLENK, HD
    ROTT, R
    [J]. VIROLOGY, 1979, 95 (01) : 197 - 207
  • [5] Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus
    Claas, ECJ
    Osterhaus, ADME
    van Beek, R
    De Jong, JC
    Rimmelzwaan, GF
    Senne, DA
    Krauss, S
    Shortridge, KF
    Webster, RG
    [J]. LANCET, 1998, 351 (9101) : 472 - 477
  • [6] SEROLOGICAL MONITORING OF EASTERN WILD TURKEYS FOR ANTIBODIES TO MYCOPLASMA SPP AND AVIAN INFLUENZA-VIRUSES
    DAVIDSON, WR
    YODER, HW
    BRUGH, M
    NETTLES, VF
    [J]. JOURNAL OF WILDLIFE DISEASES, 1988, 24 (02) : 348 - 351
  • [7] Easterday B.C., 1997, DIS POULTRY, P583, DOI DOI 10.1073/pnas.0308352100
  • [8] GUAN Y, 1997, THESIS U HONG KONG H, P105
  • [9] Characterization of the pathogenicity of members of the newly established H9N2 influenza virus lineages in Asia
    Guo, YJ
    Krauss, S
    Senne, DA
    Mo, IP
    Lo, KS
    Xiong, XP
    Norwood, M
    Shortridge, KF
    Webster, RG
    Guan, Y
    [J]. VIROLOGY, 2000, 267 (02) : 279 - 288
  • [10] MOLECULAR CHARACTERIZATION OF A NEW HEMAGGLUTININ, SUBTYPE-H14, OF INFLUENZA-A VIRUS
    KAWAOKA, Y
    YAMNIKOVA, S
    CHAMBERS, TM
    LVOV, DK
    WEBSTER, RG
    [J]. VIROLOGY, 1990, 179 (02) : 759 - 767