Chicken lines selected for their primary antibody response to sheep red blood cells show differential hypothalamic-pituitary-adrenal axis responsiveness to mild stressors

被引：11

作者：

Adriaansen-Tennekes, R. ^{[1
,2
]}

Decuypere, E. ^{[3
]}

Parmentier, H. K. ^{[2
]}

Savelkoul, H. F. J. ^{[1
]}

机构：

[1] Wageningen Univ, Dept Anim Sci, Cell Biol & Immunol Grp, NL-6709 PG Wageningen, Netherlands

[2] Wageningen Univ, Dept Anim Sci, Adaptat Physiol Grp, NL-6709 PG Wageningen, Netherlands

[3] Catholic Univ Louvain, Div Livestock Nutr Qual, B-3001 Louvain, Belgium

来源：

POULTRY SCIENCE | 2009年 / 88卷 / 09期

关键词：

corticosterone; selection line; hypothalamic-pituitary-adrenal axis; CORTICOSTERONE CONCENTRATION; INDIVIDUAL VARIATION; IMMUNE-RESPONSES; SERUM; RESISTANCE; DURATION;

D O I：

10.3382/ps.2009-00150

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The interaction between the neuroendocrine system and the immune system is well established and supports their mutually affecting relationship. Many animal selection lines have been created according to individual behavioral or neuroendocrine responses to stress. Here we present 2 chicken lines selected for 25 generations for their primary antibody response to immunization with SRBC, as well as the control line from the same parental strain. In the first experiment, the blood-sampling procedure caused a mild stress response, with the expected increase in plasma corticosterone levels. In a second experiment, group housing caused the expected increase in corticosterone levels. In both experiments, the hens of the low line showed the greatest increase in corticosterone levels to our 2 mild stressors. Our results show that birds selected throughout 25 generations for an immune parameter show different HPA axis responsiveness.

引用

页码：1879 / 1882

页数：4

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