Four cases of Hb Q-H disease found in Southern China

被引：8

作者：

Li, Dongzhi

Liao, Can

Xie, Xingmei

Zhong, Huizhu

Li, Jian

机构：

[1] Prenatal Diagnostic Center, Guangzhou Maternal and Neonatal Hospital, Guangzhou Medical College, Guangzhou, Guangdong

[2] Prenatal Diagnostic Center, Guangzhou Maternal and Neonatal Hospital, Guangzhou, Guangdong 510180

来源：

HEMOGLOBIN | 2007年 / 31卷 / 01期

关键词：

Hb H disease; Hb Q-Thailand; Hemoglobin (Hb) variant;

D O I：

10.1080/03630260601059340

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four Chinese patients with Hb Q-H disease were identified, during thalassemia screening. The main hematological characteristics of Hb Q-H disease are that Hb A is absent, and Hb Q-Thailand (also known as G-Taichung, Mahidol, Kurashiki-I and Asabara) accounts for the majority of the total hemoglobin (Hb). The phenotype of this disorder is similar to that of deletional Hb H (ss(4)) disease.

引用

页码：109 / 111

页数：3

共 4 条

[1] COMPARISON OF HEMOGLOBIN-H INCLUSION-BODIES WITH EMBRYONIC ZETA-GLOBIN IN SCREENING FOR ALPHA-THALASSEMIA [J].

CHAN, LC ;

SO, JCC ;

CHUI, DHK .

JOURNAL OF CLINICAL PATHOLOGY, 1995, 48 (09) :861-864

[2] Clinical phenotype of haemoglobin Q-H disease [J].

Leung, KFS ;

Ma, ESK ;

Chan, AYY ;

Chan, LC .

JOURNAL OF CLINICAL PATHOLOGY, 2004, 57 (01) :81-82

[3]

LIEINJO LE, 1966, BLOOD, V28, P830

[4] HB Q-THAILAND [ALPHA-74(EF3)ASP-]HIS] - GENE ORGANIZATION, MOLECULAR-STRUCTURE, AND DNA DIAGNOSIS [J].

ZENG, FY ;

FUCHAROEN, S ;

HUANG, SZ ;

RODGERS, GP .

HEMOGLOBIN, 1992, 16 (06) :481-491

← 1 →