Circulating human monocytes in the acute coronary syndrome express a characteristic proteomic profile

被引：43
作者：
Barderas, Maria G.
Tunon, Jose
Darde, Veronica M.
De la Cuesta, Fernando
Duran, Maria C.
Jimenez-Nacher, Jose J.
Tarin, Nieves
Lopez-Bescos, Lorenzo
Egido, Jesus
Vivanco, Fernando
机构：
[1] Fdn Jimenez Diaz, Dept Immunol, E-28040 Madrid, Spain
[2] Fdn Jimenez Diaz, Dept Cardiol, E-28040 Madrid, Spain
[3] Univ Autonoma Madrid, Madrid, Spain
[4] Fdn Jimenez Diaz, Renal & Vasc Lab, E-28040 Madrid, Spain
[5] Fdn Hosp Alcorcon, Cardiol Unit, Madrid, Spain
[6] Hosp Mostoles, Dept Cardiol, Madrid, Spain
[7] Univ Complutense Madrid, Proteom Unit, Dept Biochem & Mol Biol 1, Madrid, Spain
来源：
JOURNAL OF PROTEOME RESEARCH | 2007年 / 6卷 / 02期
关键词：
acute coronary syndromes; monocytes; coronary artery disease; two-dimensional electrophoresis; mass spectrometry; atherosclerosis;
D O I：
10.1021/pr0601990
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We examined the proteome of circulating monocytes of patients with acute coronary syndrome at different times in comparison to that of patients with stable coronary artery disease. On admission, the expression of 18 spot proteins was altered, 10 of which were totally absent. This pattern changed progressively, and at 6 months, there were no differences with the monocyte proteome of stable patients.
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收藏
页码：876 / 886
页数：11
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